Non-malignant hematological diseases

The non-malignant hematological diseases sections covers all aspects of non-malignant hematological diseases including basic research and therapies/clinical management of these conditions

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  1. Research article

    Comparative study of sickle cell anemia and hemoglobin SC disease: clinical characterization, laboratory biomarkers and genetic profiles

    In this study, we evaluate the association of different clinical profiles, laboratory and genetic biomarkers in patients with sickle cell anemia (SCA) and hemoglobin SC disease (HbSC) in attempt to characteriz...

    Milena Magalhães Aleluia, Teresa Cristina Cardoso Fonseca, Regiana Quinto Souza, Fábia Idalina Neves, Caroline Conceição da Guarda, Rayra Pereira Santiago, Bruna Laís Almeida Cunha, Camylla Villas Boas Figueiredo, Sânzio Silva Santana, Silvana Sousa da Paz, Júnia Raquel Dutra Ferreira, Bruno Antônio Veloso Cerqueira and Marilda de Souza Gonçalves

    BMC Hematology 2017 17:15

    Published on: 15 September 2017

  2. Research article

    Alterations in hematologic indices during long-duration spaceflight

    Although a state of anemia is perceived to be associated with spaceflight, to date a peripheral blood hematologic assessment of red blood cell (RBC) indices has not been performed during long-duration space mi...

    Hawley Kunz, Heather Quiriarte, Richard J. Simpson, Robert Ploutz-Snyder, Kathleen McMonigal, Clarence Sams and Brian Crucian

    BMC Hematology 2017 17:12

    Published on: 8 September 2017

  3. Research article

    An outline of anemia among adolescent girls in Bangladesh: findings from a cross-sectional study

    Anemia is a significant wide spread public health threat especially among the adolescent girls who are more vulnerable towards low level of hemoglobin particularly of low and middle income countries (LMICs). W...

    Sabuj Kanti Mistry, Fatema Tuz Jhohura, Fouzia Khanam, Fahmida Akter, Safayet Khan, Fakir Md Yunus, Md Belal Hossain, Kaosar Afsana, Md Raisul Haque and Mahfuzar Rahman

    BMC Hematology 2017 17:13

    Published on: 22 August 2017

  4. Research article

    Prevalence of Anaemia and Associated Risk Factors among Children in North-western Uganda: A Cross Sectional Study

    Despite the public health significance of anaemia in African children, its broader and often preventable risk factors remain largely under described. This study investigated, for the first time, the prevalence...

    Ismail Dragon Legason, Alex Atiku, Ronald Ssenyonga, Peter Olupot-Olupot and John Banson Barugahare

    BMC Hematology 2017 17:10

    Published on: 3 July 2017

  5. Research article

    Chronic complications and quality of life of patients living with sickle cell disease and receiving care in three hospitals in Cameroon: a cross-sectional study

    Sickle Cell Disease (SCD) is associated with chronic multisystem complications that significantly influence the quality of life (QOL) of patients early in their life. Although sub-Saharan Africa bears 75% of t...

    Anne M. Andong, Eveline D. T. Ngouadjeu, Cavin E. Bekolo, Vincent S. Verla, Daniel Nebongo, Yannick Mboue-Djieka and Simeon-Pierre Choukem

    BMC Hematology 2017 17:7

    Published on: 20 April 2017

  6. Research article

    Sickle-cell disease in febrile children living in a rural village of Madagascar and association with malaria and respiratory infections

    In Madagascar, the last study on sickle cell disease (SCD) was done in the early 1980s. The country is known as endemic for malaria and respiratory infections. The main objective of this study was to estimate ...

    Muriel N. Maeder, Henintsoa M. Rabezanahary, Norosoa J. Zafindraibe, Martin Raoelina Randriatiana, Tahinamandranto Rasamoelina, Andry T. Rakotoarivo, Philippe Vanhems, Jonathan Hoffmann, Thomas Bénet, Mala Rakoto Andrianarivelo and Olivat A. Rakoto-Alson

    BMC Hematology 2016 16:30

    Published on: 1 December 2016

  7. Research article

    Prevalence of transfusion transmissible infections in blood donors of Pakistan

    Transfusion-transmitted infections threaten the safety of patients requiring blood transfusion, which in turn imposes serious challenges for the availability of safe blood products that are still affordable in...

    Aisha Arshad, Munira Borhany, Nida Anwar, Imran Naseer, Rehan Ansari, Samson Boota, Naveena Fatima, Mustansir Zaidi and Tahir Shamsi

    BMC Hematology 2016 16:27

    Published on: 18 November 2016

  8. Study protocol

    A randomized controlled trial studying the effectiveness of group medical appointments on self-efficacy and adherence in sickle cell disease (TEAM study): study protocol

    Sickle cell disease (SCD) is endemic in non-Western countries. Due to migration, the prevalence of SCD in the Netherlands has increased. Adherence to medical treatment is recognized as a major problem area. Th...

    Marlous J. Madderom, Jessica Heijdra, Elisabeth M. W. J. Utens, Suzanne Polinder, Anita W. Rijneveld and Marjon H. Cnossen

    BMC Hematology 2016 16:21

    Published on: 4 August 2016

  9. Research article

    Ferumoxytol versus iron sucrose treatment: a post-hoc analysis of randomized controlled trials in patients with varying renal function and iron deficiency anemia

    Iron deficiency anemia is highly prevalent in patients with chronic kidney disease and is often treated with intravenous iron. There are few trials directly comparing the safety and efficacy of different intra...

    William E. Strauss, Naomi V. Dahl, Zhu Li, Gloria Lau and Lee F. Allen

    BMC Hematology 2016 16:20

    Published on: 26 July 2016

  10. Research article

    Prevalence of neutropenia in children by nationality

    A high prevalence of neutropenia has been reported in several ethnic groups amongst whom many healthy individuals with low neutrophil counts undergo unnecessary investigations. This study aims to ascertain the...

    Srdjan Denic, Hassib Narchi, Lolowa A. Al Mekaini, Suleiman Al-Hammadi, Omar N. Al Jabri and Abdul-Kader Souid

    BMC Hematology 2016 16:15

    Published on: 21 May 2016

  11. Research article

    Randomized double-blind safety comparison of intravenous iron dextran versus iron sucrose in an adult non-hemodialysis outpatient population: A feasibility study

    Intravenous iron therapy is a treatment option for iron deficient patients who are intolerant to oral iron or where oral iron is ineffective, but with possible adverse effects. Currently, prospective studies c...

    Martha L. Louzada, Cyrus C. Hsia, Fatimah Al-Ani, Fiona Ralley, Anargyros Xenocostas, Janet Martin, Sarah E. Connelly, Ian H. Chin-Yee, Leonard Minuk and Alejandro Lazo-Langner

    BMC Hematology 2016 16:7

    Published on: 11 March 2016

  12. Research article

    Prevalence and correlates of anemia among HIV infected patients on highly active anti-retroviral therapy at Zewditu Memorial Hospital, Ethiopia

    Ethiopia is one of the most seriously HIV affected countries in Sub-Saharan Africa. Anemia is a known predictor of disease progression and death among HIV infected patients. In this study, we investigated the ...

    Muluken Assefa, Woldaregay Erku Abegaz, Aster Shewamare, Girmay Medhin and Mulugeta Belay

    BMC Hematology 2015 15:6

    Published on: 30 April 2015

  13. Case report

    Case report: paroxysmal cold hemoglobinuria presenting during pregnancy

    Paroxysmal cold hemoglobinuria is caused by a biphasic IgG autoantibody that triggers complement-mediated intravascular hemolysis. Paroxysmal cold hemoglobinuria has not previously been reported to occur in as...

    Andrea O Akpoguma, Thomas L Carlisle and Steven R Lentz

    BMC Hematology 2015 15:3

    Published on: 13 February 2015

  14. Case report

    Severe congenital neutropenia caused by the ELANE gene mutation in a Vietnamese boy with misdiagnosis of tuberculosis and autoimmune neutropenia: a case report

    Severe congenital neutropenia (SCN) is an immunodeficiency disease characterized low blood neutrophil counts, early bacterial infections, and risk of leukaemia development. Heterozygous mutations in the ELANE gen...

    Quang Van Vu, Taizo Wada, Tham Thi Tran, Duc Ngoc Ngo, Thuc Van Dinh, Cuong Hung Nguyen, Huong Thi Minh Le, Akihiro Yachie and Sang Ngoc Nguyen

    BMC Hematology 2015 15:2

    Published on: 24 January 2015

  15. Research article

    Profile of blood cell abnormalities among antiretroviral therapy naïve HIV patients attending the Yaounde University Teaching Hospital, Cameroon

    Abnormal hemograms are common manifestations and important predictive tools for morbidity in the human immunodeficiency virus (HIV) infection. Few studies have been reported on the blood profile of HIV antiret...

    Paul Nji Wankah, Claude Tayou Tagny and Dora Ngum Shu Mbanya

    BMC Hematology 2014 14:15

    Published on: 8 September 2014

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