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Hemostasis, thrombosis and vascular biology

Section edited by Alejandro Lazo-Langner

The hemostasis, thrombosis and vascular biology section deals with all aspects, basic research and clinical, of vascular biology including thrombosis and hemostasis

  1. Massive bleeding is one of the commonest salvageable causes of death. The search for an ideal haemostatic agent during massive bleeding is still ongoing. One of the novel haemostatic medications is recombinant...

    Authors: Nurfatin Mohd Shah, Soon Eu Chong, Syahirah Mohamed Yusoff, Mohd Zulfakar Mazlan, Khairul Bariah Johan, Nizuwan Azman, Jo Anne Lim, Siti Mardhiana Mohamad, Siti Salmah Noordin, Zainab Abdul Ghaffar, Mohd Hasyizan Hassan, Muhammad Azrul Zabidi and Nur Arzuar Abdul Rahim
    Citation: BMC Hematology 2018 18:34
  2. In sub-Saharan Africa where sickle cell trait (SCT) and malaria is prevalent, significant proportions of blood donors may be affected by one or more of these abnormalities. The haemato-biochemical properties o...

    Authors: Enoch Aninagyei, Emmanuel Tetteh Doku, Patrick Adu, Alexander Egyir-Yawson and Desmond Omane Acheampong
    Citation: BMC Hematology 2018 18:30
  3. The acquired inhibitors of coagulation have been observed in very rare cases of monoclonal gammopathies. We report a very rare case of anti-factor XI antibodies in patient with plasma cell leukemia (PCL).

    Authors: Jean Uwingabiye, Hafid Zahid, Mohamed El Amrani, Fayçal Labrini, Abdelhak Elkhazraji, Driss El Kabbaj, Mohammed Benyahia, Anass Yahyaoui, Rachid Hadef and Nezha Messaoudi
    Citation: BMC Hematology 2018 18:18
  4. Abnormal fibrinogens can be caused by clinically silent hereditary mutations. A new case was detected accidentally in an 11-year-old girl when routine pre-operative coagulation tests were performed for nasal t...

    Authors: R. Marchi, M. Linares, H. Rojas, A. Ruiz-Sáez, M. Meyer, A. Casini and S.O. Brennan
    Citation: BMC Hematology 2017 17:22
  5. Blood can save millions of lives. Even though people do not donate blood regularly, there is a constant effort to balance the supply and demand of blood. The aim of this study was, therefore, to determine the ...

    Authors: Habtom Woldeab Gebresilase, Robera Olana Fite and Sileshi Garoma Abeya
    Citation: BMC Hematology 2017 17:20
  6. It has been reported that patients with SCD do have an abnormal coagulation profile. Coagulopathy is thought to be one of the key factors that contribute to the vaso-occlusive crisis that characterises sickle ...

    Authors: Shiekh Awoda, Ahmed A. Daak, Nazik Elmalaika Husain, Kebreab Ghebremeskel and Mustafa I. Elbashir
    Citation: BMC Hematology 2017 17:18
  7. Circumcision in hemophiliacs is a delicate surgery because of bleeding risks that could be avoided by adequate substitution of coagulation factor. This practice is very challenging in countries where anti hemo...

    Authors: Moussa Seck, Aloïse Sagna, Mame Sokhna Guéye, Blaise Félix Faye, Diariétou Sy, Sokhna Aissatou Touré, Abibatou Sall, Awa Oumar Touré and Saliou Diop
    Citation: BMC Hematology 2017 17:8
  8. Familial and acquired thrombophilia are often etiologic for idiopathic hip and jaw osteonecrosis (ON), and testosterone therapy (TT) can interact with thrombophilia, worsening ON.

    Authors: Michael Ian Jarman, Kevin Lee, Ariel Kanevsky, Sarah Min, Ilana Schlam, Chris Mahida, Ali Huda, Alexander Milgrom, Naila Goldenberg, Charles J. Glueck and Ping Wang
    Citation: BMC Hematology 2017 17:5
  9. When availability and/or affordability of anti-hemophilic factor concentrates are limited, optimal prophylaxis regimens in severe hemophilia A (HA) remain to be determined. In selected situations, low-dose dai...

    Authors: Terry Mizrahi, Jean St-Louis, Nancy L. Young, Francine Ménard, Nichan Zourikian, Evemie Dubé and Georges E. Rivard
    Citation: BMC Hematology 2016 16:26
  10. Anticoagulant therapy is prescribed for millions of patients worldwide for the prevention and treatment of both arterial and venous thrombosis. Historically, only vitamin K antagonists have been available for ...

    Authors: Vivian Auyeung, Jignesh P. Patel, John K. Abdou, Bipin Vadher, Lynda Bonner, Alison Brown, Lara N. Roberts, Raj K. Patel and Roopen Arya
    Citation: BMC Hematology 2016 16:22
  11. Bone marrow examination may be required to discriminate causes of thrombocytopenia as hypoproductive or hyperdestructive. However, this procedure is invasive and time consuming. This study assessed the diagnos...

    Authors: Mikias Negash, Aster Tsegaye and Amha G/Medhin
    Citation: BMC Hematology 2016 16:18
  12. Tuberculosis (TB) and HIV are among the risk factors for deep vein thrombosis (DVT). There are several challenges in the management of DVT patients with TB-HIV co-infection including drug-drug interactions and...

    Authors: C Sekaggya, D Nalwanga, A Von Braun, R Nakijoba, A Kambugu, J Fehr, M Lamorde and B Castelnuovo
    Citation: BMC Hematology 2016 16:16
  13. This study was undertaken to explore the longitudinal patterns of health-related quality of life (HRQoL) among youth and young adults with Hemophilia A (HA) over a 3-year period. This report presents the basel...

    Authors: J. St-Louis, D. J. Urajnik, F. Ménard, S. Cloutier, R. J. Klaassen, B. Ritchie, G. E. Rivard, M. Warner, V. Blanchette and N. L. Young
    Citation: BMC Hematology 2016 16:13
  14. Fibrin provides a temporary matrix at the site of vascular injury. The aims of the present work were (1) to follow fibrin formation and lysis onto the surface of human dermal microvascular endothelial cells (H...

    Authors: O. Castillo, H. Rojas, Z. Domínguez, E. Anglés-Cano and R. Marchi
    Citation: BMC Hematology 2016 16:9
  15. In patients hospitalized over a 4 year period for pulmonary embolism (PE), we assessed relationships of testosterone (TT) and estrogen therapy (ET) anteceding PE in patients found to have familial-acquired thr...

    Authors: Marloe Prince, Charles J. Glueck, Parth Shah, Ashwin Kumar, Michael Goldenberg, Matan Rothschild, Nasim Motayar, Vybhav Jetty, Kevin Lee and Ping Wang
    Citation: BMC Hematology 2016 16:6
  16. Patients receiving anticoagulant drugs must be carefully screened for drug-related problems, as such medications, including warfarin have narrow therapeutic ranges and a high potential for complications. Thus,...

    Authors: Fekede Bekele Daba, Fisihatsion Tadesse and Ephrem Engidawork
    Citation: BMC Hematology 2016 16:2
  17. Direct oral anticoagulants (DOACs) are now standard of care for the management of thromboembolic risk. A prevalent issue of concern is how to manage direct oral anticoagulant (DOAC)-associated bleeding for whi...

    Authors: Michelle Sholzberg, Katerina Pavenski, Nadine Shehata, Christine Cserti-Gazdewich and Yulia Lin
    Citation: BMC Hematology 2015 15:18
  18. Although prophylaxis is a standard of care for young children in developed countries, known to reduce the severity of hemophilic arthropathy, older adults with existing arthropathy have not traditionally used ...

    Authors: Shannon C Jackson, Ming Yang, Leonard Minuk, Michelle Sholzberg, Jean St-Louis, Alfonso Iorio, Robert Card and Man-Chiu Poon
    Citation: BMC Hematology 2015 15:4
  19. Hemophilia A (HA) is an X-linked inherited bleeding disorder, resulting from a qualitative or quantitative deficiency of clotting factor VIII (FVIII). Antibodies against FVIII, also called inhibitors, block th...

    Authors: Amanda CO Silveira, Marcio AP Santana, Isabella G Ribeiro, Daniel G Chaves and Olindo A Martins-Filho
    Citation: BMC Hematology 2015 15:1
  20. Reliable central venous access (CVC) is essential for hematology–oncology patients since frequent puncture of peripheral veins—e.g., for chemotherapy, antibiotic administration, repeated blood sampling, and mo...

    Authors: Verena Wiegering, Sophie Schmid, Oliver Andres, Clemens Wirth, Armin Wiegering, Thomas Meyer, Beate Winkler, Paul G Schlegel and Matthias Eyrich
    Citation: BMC Hematology 2014 14:18