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  1. Content type: Research article

    Blood can only be given from generous donors. The main objective of this study was to assess the knowledge, attitude and practice (KAP) and associated factors of blood donation among health care workers in Wol...

    Authors: Dawit Malako, Fissehatsion Yoseph and Mebratu Legesse Bekele

    Citation: BMC Hematology 2019 19:10

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  2. Content type: Research article

    Sickle cell disease (SCD) is a chronic hematologic disease associated with increased morbidity and mortality. Hemoglobinopathies are the most prevalent genetic disease globally, and SCD is estimated to affect ...

    Authors: David Muthahi Kambasu, Joseph Rujumba, Hervé Monka Lekuya, Deogratias Munube and Ezekiel Mupere

    Citation: BMC Hematology 2019 19:9

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  3. Content type: Research article

    Even though the incidences of hematologic malignancies have received considerable attentions globally, there is paucity of information on patterns of hematologic malignancy in Eritrea. The study was conducted ...

    Authors: Natnael Belai, Amon Solomon Ghebrenegus, Anim Ata Alamin, Ghirmay Embaye and Amanuel Kidane Andegiorgish

    Citation: BMC Hematology 2019 19:8

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  4. Content type: Research article

    The BCR-ABL1 fusion gene underlying the pathogenesis of CML can arise from a variety of breakpoints. The e13a2 and e14a2 transcripts formed by breakpoints occurring around exon 13 and exon 14 of the BCR gene resp...

    Authors: Graeme Greenfield, Ross McMullan, Nuala Robson, Julie McGimpsey, Mark Catherwood and Mary Frances McMullin

    Citation: BMC Hematology 2019 19:7

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  5. Content type: Research article

    Anemia, defined as a low blood hemoglobin concentration, has been shown to be a major public health concern in low-income countries like Ethiopia. School-age children are the most vulnerable population groups ...

    Authors: Eshetu Zerihun Tariku, Getaneh Alemu Abebe, Zeleke Aschalew Melketsedik, Befikadu Tariku Gutema, Nega Degefa Megersa, Muluken Bekele Sorrie, Feleke Gebremeskel Weldehawariat and Eskeziyaw Agedew Getahun

    Citation: BMC Hematology 2019 19:6

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  6. Content type: Research article

    Transfusion-transmissible infections pose a major health risk in developing countries, including Eritrea. In the present study, we sought to determine the prevalence of specific transfusion transmitted infecti...

    Authors: Yacob Tesfamichael Keleta, Oliver Okoth Achila, Absera Woldu Haile, Bereket Habteslasie Gebrecherkos, Danait Tareke Tesfaldet, Kibrom Solomon Teklu, Mesuda Abrhum Mohammed and Selihom Tesfaslase Ghedel

    Citation: BMC Hematology 2019 19:5

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  8. Content type: Research article

    The serum ferritin assay is recommended in Sickle Cell Anemia (SCA) patients receiving regular transfusions. According to several authors, elevated iron stores indicating iron chelation corresponds to hyperfer...

    Authors: Jean-Robert Makulo, Karen Efombola Itokua, Rosette Kevani Lepira, Gloire Mavinga Bundutidi, Michel Ntetani Aloni, René Makuala Ngiyulu, Jean Lambert Gini and François Bompeka Lepira

    Citation: BMC Hematology 2019 19:3

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  9. Content type: Research article

    Hemoglobin A1C (HbA1c) is the predominant hemoglobin found in HbA1 fractions. A1c assay is the recommended assay for diagnosing diabetes and any condition that changes red cell turnover such as Iron deficiency...

    Authors: Absra Solomon, Mintewab Hussein, Mikias Negash, Abdurezak Ahmed, Fitsum Bekele and Daniel Kahase

    Citation: BMC Hematology 2019 19:2

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  12. Content type: Research article

    Early detection and treatment of iron deficiency during pregnancy is crucial for optimum pregnancy outcomes. Anaemia is a late indictor of iron deficiency measured as Hb < 11 g/dL, and is widely used as a prox...

    Authors: Miruna Sudharshani Kalaimani Rabindrakumar, V. Pujitha Wickramasinghe, Lallindra Gooneratne, Carukshi Arambepola, Hemantha Senanayake and Tharanga Thoradeniya

    Citation: BMC Hematology 2018 18:37

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  13. Content type: Research article

    Blood transfusion is an essential component of the health care system of every country and patients who require blood transfusion service as part of the clinical management of their condition have the right to...

    Authors: Shamsudeen Mohammed and Harry Barton Essel

    Citation: BMC Hematology 2018 18:36

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  14. Content type: Research article

    Infection is a major complication in aplastic anemia (AA) patients. Primary objectives of this study were to determine the prevalence of infections and to determine types of pathogens associated with infection...

    Authors: Rapee Lertpongpiroon, Ekarat Rattarittamrong, Thanawat Rattanathammethee, Chatree Chai-Adisaksopha, Adisak Tantiworawit, Parichat Salee and Lalita Norasetthada

    Citation: BMC Hematology 2018 18:35

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  15. Content type: Research article

    Massive bleeding is one of the commonest salvageable causes of death. The search for an ideal haemostatic agent during massive bleeding is still ongoing. One of the novel haemostatic medications is recombinant...

    Authors: Nurfatin Mohd Shah, Soon Eu Chong, Syahirah Mohamed Yusoff, Mohd Zulfakar Mazlan, Khairul Bariah Johan, Nizuwan Azman, Jo Anne Lim, Siti Mardhiana Mohamad, Siti Salmah Noordin, Zainab Abdul Ghaffar, Mohd Hasyizan Hassan, Muhammad Azrul Zabidi and Nur Arzuar Abdul Rahim

    Citation: BMC Hematology 2018 18:34

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  16. Content type: Research article

    Africa has the highest burden of Sickle cell disease (SCD) but there are few large, systematic studies providing reliable descriptions of the disease spectrum. Tanzania, with 11,000 SCD births annually, establ...

    Authors: Julie Makani, Furahini Tluway, Abel Makubi, Deogratius Soka, Siana Nkya, Raphael Sangeda, Josephine Mgaya, Stella Rwezaula, Fenella J. Kirkham, Christina Kindole, Elisha Osati, Elineema Meda, Robert W. Snow, Charles R. Newton, David Roberts, Muhsin Aboud…

    Citation: BMC Hematology 2018 18:33

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  17. Content type: Research article

    Anemia is a common hematologic disorder among human Immunodeficiency virus (HIV) infected adult Individuals. However, there is no concrete scientific evidence established at national level in Ethiopia. Hence, ...

    Authors: Ayenew Negesse, Temesgen Getaneh, Habtamu Temesgen, Tesfahun Taddege, Dube Jara and Zeleke Abebaw

    Citation: BMC Hematology 2018 18:32

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  18. Content type: Research article

    Anemia during pregnancy is a public health problem especially in developing countries and it is associated with maternal and perinatal adverse outcomes. There is no meta-analysis on anemia during pregnancy in ...

    Authors: Ishag Adam, Yassin Ibrahim and Osama Elhardello

    Citation: BMC Hematology 2018 18:31

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  19. Content type: Research article

    In sub-Saharan Africa where sickle cell trait (SCT) and malaria is prevalent, significant proportions of blood donors may be affected by one or more of these abnormalities. The haemato-biochemical properties o...

    Authors: Enoch Aninagyei, Emmanuel Tetteh Doku, Patrick Adu, Alexander Egyir-Yawson and Desmond Omane Acheampong

    Citation: BMC Hematology 2018 18:30

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  20. Content type: Research article

    An individual with visceral Leishmaniasis (VL) commonly present with anemia and one of the VL treatment center in northwest Ethiopia has been recommended iron-folic acid supplementation to these patients. But ...

    Authors: Tadele Mulaw, Amare Tariku, Adino Tesfahun Tsegaye and Zegeye Abebe

    Citation: BMC Hematology 2018 18:29

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  21. Content type: Research article

    Idiopathic (immune) thrombocytopenic purpura (ITP) is an acquired disorder characterized by autoantibodies against platelet membrane antigens. Several studies found an association between Helicobacter Pylori i...

    Authors: Sara Aljarad, Ahmad Alhamid, Ahmad Sankari Tarabishi, Ameen Suliman and Ziad Aljarad

    Citation: BMC Hematology 2018 18:28

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  22. Content type: Research article

    Anemia in pregnancy may not only be associated with maternal morbidity and mortality but can also be detrimental to the fetus. A definitive diagnosis of anemia is a pre-requisite to unravelling possible cause(...

    Authors: Benjamin Ahenkorah, Kwabena Nsiah, Peter Baffoe and Enoch Odame Anto

    Citation: BMC Hematology 2018 18:27

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  23. Content type: Research article

    Sickle cell disease (SCD) accounts for 5% of mortality in African children aged < 5 years. Improving the care management and quality of life of patients with SCD requires a reliable diagnosis in resource-limit...

    Authors: Akueté Yvon Segbena, Aldiouma Guindo, Romain Buono, Irénée Kueviakoe, Dapa A. Diallo, Gregory Guernec, Mouhoudine Yerima, Pierre Guindo, Emilie Lauressergues, Aude Mondeilh, Valentina Picot and Valériane Leroy

    Citation: BMC Hematology 2018 18:26

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  24. Content type: Research article

    Sickle cell anaemia (SCA) is prevalent in sub-Saharan Africa, with high risk of complications requiring emergency care. There is limited information about presentation of patients with SCA to hospitals for eme...

    Authors: Hendry R. Sawe, Teri A. Reynolds, Juma A. Mfinanga, Michael S. Runyon, Brittany L. Murray, Lee A. Wallis and Julie Makani

    Citation: BMC Hematology 2018 18:25

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  25. Content type: Research article

    The use of unscreened blood exposes the patient to many transfusion transmitted infections including Hepatitis B Virus (HBV), Hepatitis C virus (HCV), Human Immunodeficiency Virus (HIV), and syphilis, among ot...

    Authors: Zelalem Teklemariam, Habtamu Mitiku and Fitsum Weldegebreal

    Citation: BMC Hematology 2018 18:24

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  26. Content type: Research article

    Sickle Cell Anemia (SCA) is characterized by high levels of oxidative stress markers and low levels of antioxidant capacity. Antioxidant defence mechanisms against the harmful effects of ROS requires cellular ...

    Authors: Olivier Mukuku, Joseph K. Sungu, Augustin Mulangu Mutombo, Paul Makan Mawaw, Michel Ntetani Aloni, Stanislas Okitotsho Wembonyama and Oscar Numbi Luboya

    Citation: BMC Hematology 2018 18:23

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  27. Content type: Research article

    Tumor lysis syndrome (TLS) is a life-threatening emergency disorder, caused by an abrupt release of intracellular metabolites after tumor cell death. It is characterized by a series of metabolic manifestations...

    Authors: Haileleul Micho, Yasin Mohammed, Daniel Hailu and Solomon Genet

    Citation: BMC Hematology 2018 18:22

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  28. Content type: Case report

    Chromosomal abnormalities are diagnostic and prognostic key factors in acute myeloid leukemia (AML) patients, as they play a central role for risk stratification algorithms. High hyperdiploidy (HH), a rare cyt...

    Authors: Abdulsamad Wafa, Suher ALmedania, Abdulmunim Aljapawe, Thomas Liehr, Soulaiman E. Soulaiman, Raja Mouna, Moneeb A. K. Othman and Walid ALachkar

    Citation: BMC Hematology 2018 18:21

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  29. Content type: Research article

    Dengue infection patients are presented with acute febrile illness. Clinical presentations may mimic other infections. The serology for definite diagnosis is costly and inaccessible in many hospitals. We sough...

    Authors: Juthatip Chaloemwong, Adisak Tantiworawit, Thanawat Rattanathammethee, Sasinee Hantrakool, Chatree Chai-Adisaksopha, Ekarat Rattarittamrong and Lalita Norasetthada

    Citation: BMC Hematology 2018 18:20

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  30. Content type: Research article

    In patients presenting with peripheral lymphadenopathy, it is critical to effectively identify those with underlying cancer who require urgent specialist care.

    Authors: Andrea Kühnl, David Cunningham, Margaret Hutka, Clare Peckitt, Hamoun Rozati, Federica Morano, Irene Chong, Angela Gillbanks, Andrew Wotherspoon, Michelle Harris, Tracey Murray and Ian Chau

    Citation: BMC Hematology 2018 18:19

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  31. Content type: Case report

    The acquired inhibitors of coagulation have been observed in very rare cases of monoclonal gammopathies. We report a very rare case of anti-factor XI antibodies in patient with plasma cell leukemia (PCL).

    Authors: Jean Uwingabiye, Hafid Zahid, Mohamed El Amrani, Fayçal Labrini, Abdelhak Elkhazraji, Driss El Kabbaj, Mohammed Benyahia, Anass Yahyaoui, Rachid Hadef and Nezha Messaoudi

    Citation: BMC Hematology 2018 18:18

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  33. Content type: Research article

    An insight into the utilization pattern helps in future planning of blood drive. This study was conducted to describe the demographic characteristics of the transfusion recipients and pattern of blood and bloo...

    Authors: Henshaw Uchechi Okoroiwu and Ifeyinwa Maryann Okafor

    Citation: BMC Hematology 2018 18:16

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  34. Content type: Research article

    In pregnancy, hematological changes occur in order to meet the demands of the developing fetus and placenta, with major alterations in blood volume. Abnormal hematological profile affects pregnancy and its out...

    Authors: Angesom Gebreweld, Delayehu Bekele and Aster Tsegaye

    Citation: BMC Hematology 2018 18:15

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  35. Content type: Research article

    Anemia affects a significant part of the population in nearly every country in the globe. Iron requirements are greatest at ages 6–23 months when growth is extremely rapid and critically essential in critical ...

    Authors: Bereket Geze Malako, Melese Sinaga Teshome and Tefera Belachew

    Citation: BMC Hematology 2018 18:14

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  37. Content type: Research article

    Evidence-based guidelines for sickle cell disease (SCD) health maintenance and management have been developed for primary health care providers, but not for individuals with SCD. To improve the quality of care...

    Authors: Robert Michael Cronin, Tilicia L. Mayo-Gamble, Sarah-Jo Stimpson, Sherif M. Badawy, Lori E. Crosby, Jeannie Byrd, Emmanuel J. Volanakis, Adetola A. Kassim, Jean L. Raphael, Velma M. Murry and Michael R. DeBaun

    Citation: BMC Hematology 2018 18:12

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  39. Content type: Debate

    Blood transfusions are often essential for treatment of severe anaemia and pregnancy complications. The unavailability of blood is a medical concern, especially in developing countries. New sources of red bloo...

    Authors: Maria Teresa Esposito

    Citation: BMC Hematology 2018 18:10

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  40. Content type: Research article

    Hematological abnormalities are common in HIV positive patients. Of these, thrombocytopenia is a known complication which has been associated with a variety of bleeding disorders. However, its magnitude and re...

    Authors: Gashaw Garedew Woldeamanuel and Diresibachew Haile Wondimu

    Citation: BMC Hematology 2018 18:9

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  41. Content type: Research article

    In individuals infected with HIV, hematological abnormalities are common and are associated with increased risk of disease progression and death. However, the profile of hematological abnormalities in HIV infe...

    Authors: Tamirat Edie Fekene, Leja Hamza Juhar, Chernet Hailu Mengesha and Dawit Kibru Worku

    Citation: BMC Hematology 2018 18:8

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  42. Content type: Research article

    Anemia is the most common hematological abnormality in Human immunodeficiency virus (HIV) positive patients and a significant predictor of its progression to AIDS or death. This study was aimed to assess the p...

    Authors: Gashaw Garedew Woldeamanuel and Diresibachew Haile Wondimu

    Citation: BMC Hematology 2018 18:7

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  43. Content type: Research article

    Immunophenotypic analysis of the bone marrow (BM) cells has proven to be helpful in the diagnosis of Myelodysplastic Syndromes (MDS). However, the usefulness of flow cytometry (FCM) for the detection of myelod...

    Authors: Ana Aires, Maria dos Anjos Teixeira, Catarina Lau, Cláudia Moreira, Ana Spínola, Alexandra Mota, Inês Freitas, Jorge Coutinho and Margarida Lima

    Citation: BMC Hematology 2018 18:6

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  45. Content type: Commentary

    Myelodysplastic syndromes (MDS) encompass a diverse group of hematologic disorders characterized by ineffective and malignant hematopoiesis, peripheral cytopenias and significantly increased risk of progressio...

    Authors: Rory M. Shallis and Amer M. Zeidan

    Citation: BMC Hematology 2018 18:4

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  49. Content type: Research article

    Abnormal fibrinogens can be caused by clinically silent hereditary mutations. A new case was detected accidentally in an 11-year-old girl when routine pre-operative coagulation tests were performed for nasal t...

    Authors: R. Marchi, M. Linares, H. Rojas, A. Ruiz-Sáez, M. Meyer, A. Casini and S.O. Brennan

    Citation: BMC Hematology 2017 17:22

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  50. Content type: Research article

    Hypertension is a major health problem worldwide. It can lead to cardiovascular disease and also leads to functional disturbances including hematological parameters. The abnormalities of haematological paramet...

    Authors: Bamlaku Enawgaw, Nigist Adane, Betelihem Terefe, Fikir Asrie and Mulugeta Melku

    Citation: BMC Hematology 2017 17:21

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