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BMC Hematology


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  1. Content type: Research article

    Sickle cell anemia patients suffer from oxidative stress due to chronic inflammation and self-oxidation of sickle hemoglobin (Hb S). Chronic oxidative stress contributes to endothelial dysfunction, inflammatio...

    Authors: Lamis Kaddam, Imad Fadl-Elmula, Omer Ali Eisawi, Haydar Awad Abdelrazig, Mohammed Abdelraman Salih, Florian Lang and Amal M. Saeed

    Citation: BMC Hematology 2017 17:4

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  2. Content type: Case report

    Chronic lymphocytic leukemia (CLL) is the most common leukemia in Western countries. The frequency of symptomatic central nervous system (CNS) involvement is unknown but thought to be a rare phenomenon. Curren...

    Authors: Cristhiam M. Rojas-Hernandez, Jacklyn Nemunaitis, Kristopher D. Marjon, Daniel Bustamante, Qian-Yun Zhang and Jennifer M. Gillette

    Citation: BMC Hematology 2017 17:3

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  3. Content type: Research article

    Malaria and human immunodeficiency virus are the two most devastating global health problems causing more than two million deaths each year. Hematological abnormalities such as anemia, thrombocytopenia and leu...

    Authors: Tsion Sahle, Tilahun Yemane and Lealem Gedefaw

    Citation: BMC Hematology 2017 17:2

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  4. Content type: Research article

    Anemia is a strong predictor of mortality and poor quality of life among persons with either renal impairment or HIV infection. In this study, we investigated the prevalence of anemia and its association with ...

    Authors: Temesgen Fiseha, Zemenu Tamir, Abdurahaman Seid and Wondmagegn Demsiss

    Citation: BMC Hematology 2017 17:1

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  5. Content type: Research article

    In Madagascar, the last study on sickle cell disease (SCD) was done in the early 1980s. The country is known as endemic for malaria and respiratory infections. The main objective of this study was to estimate ...

    Authors: Muriel N. Maeder, Henintsoa M. Rabezanahary, Norosoa J. Zafindraibe, Martin Raoelina Randriatiana, Tahinamandranto Rasamoelina, Andry T. Rakotoarivo, Philippe Vanhems, Jonathan Hoffmann, Thomas Bénet, Mala Rakoto Andrianarivelo and Olivat A. Rakoto-Alson

    Citation: BMC Hematology 2016 16:30

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  6. Content type: Case report

    Hemophagocytic lymphohistiocytosis in adults is often secundary to an infection or a neoplasm. In this last case, T cell lymphomas are the most frequent causes. Hemophagocytic lymphohistiocytosis secundary to ...

    Authors: El Mehdi Mahtat, Maryem Zine, Mohamed Allaoui, Malika Kerbout, Nezha Messaoudi, Kamal Doghmi and Mohamed Mikdame

    Citation: BMC Hematology 2016 16:28

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  7. Content type: Research article

    Transfusion-transmitted infections threaten the safety of patients requiring blood transfusion, which in turn imposes serious challenges for the availability of safe blood products that are still affordable in...

    Authors: Aisha Arshad, Munira Borhany, Nida Anwar, Imran Naseer, Rehan Ansari, Samson Boota, Naveena Fatima, Mustansir Zaidi and Tahir Shamsi

    Citation: BMC Hematology 2016 16:27

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  8. Content type: Research article

    When availability and/or affordability of anti-hemophilic factor concentrates are limited, optimal prophylaxis regimens in severe hemophilia A (HA) remain to be determined. In selected situations, low-dose dai...

    Authors: Terry Mizrahi, Jean St-Louis, Nancy L. Young, Francine Ménard, Nichan Zourikian, Evemie Dubé and Georges E. Rivard

    Citation: BMC Hematology 2016 16:26

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  9. Content type: Research article

    Since the discovery of specific histocompatibility, literature has associated genes involved in the immune response, like the Human Leucocyte Antigen (HLA), with a better prognosis in transplantation. However,...

    Authors: Daniele Kazue Sugioka, Carlos Eduardo Ibaldo Gonçalves and Maria da Graça Bicalho

    Citation: BMC Hematology 2016 16:25

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  10. Content type: Research article

    Although the demand for blood supply has progressively increased in developing countries, evidences indicate that there is a major shortage of blood and blood products in these countries, particularly in Ethio...

    Authors: Yenework Acham Jemberu, Ahmed Esmael and Kedir Y. Ahmed

    Citation: BMC Hematology 2016 16:23

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  11. Content type: Study protocol

    Anticoagulant therapy is prescribed for millions of patients worldwide for the prevention and treatment of both arterial and venous thrombosis. Historically, only vitamin K antagonists have been available for ...

    Authors: Vivian Auyeung, Jignesh P. Patel, John K. Abdou, Bipin Vadher, Lynda Bonner, Alison Brown, Lara N. Roberts, Raj K. Patel and Roopen Arya

    Citation: BMC Hematology 2016 16:22

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  12. Content type: Study protocol

    Sickle cell disease (SCD) is endemic in non-Western countries. Due to migration, the prevalence of SCD in the Netherlands has increased. Adherence to medical treatment is recognized as a major problem area. Th...

    Authors: Marlous J. Madderom, Jessica Heijdra, Elisabeth M. W. J. Utens, Suzanne Polinder, Anita W. Rijneveld and Marjon H. Cnossen

    Citation: BMC Hematology 2016 16:21

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  13. Content type: Research article

    Iron deficiency anemia is highly prevalent in patients with chronic kidney disease and is often treated with intravenous iron. There are few trials directly comparing the safety and efficacy of different intra...

    Authors: William E. Strauss, Naomi V. Dahl, Zhu Li, Gloria Lau and Lee F. Allen

    Citation: BMC Hematology 2016 16:20

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  14. Content type: Research article

    Bone marrow examination may be required to discriminate causes of thrombocytopenia as hypoproductive or hyperdestructive. However, this procedure is invasive and time consuming. This study assessed the diagnos...

    Authors: Mikias Negash, Aster Tsegaye and Amha G/Medhin

    Citation: BMC Hematology 2016 16:18

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  15. Content type: Research article

    Survival analysis is commonly used to determine the treatment effect among acute lymphoblastic leukemia (ALL) patients who undergo allogeneic stem cell transplantation (allo-SCT) or other treatments. The aim o...

    Authors: Chatree Chai-Adisaksopha, Alfonso Iorio, Christopher Hillis, Wendy Lim and Mark Crowther

    Citation: BMC Hematology 2016 16:17

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  16. Content type: Research article

    Tuberculosis (TB) and HIV are among the risk factors for deep vein thrombosis (DVT). There are several challenges in the management of DVT patients with TB-HIV co-infection including drug-drug interactions and...

    Authors: C Sekaggya, D Nalwanga, A Von Braun, R Nakijoba, A Kambugu, J Fehr, M Lamorde and B Castelnuovo

    Citation: BMC Hematology 2016 16:16

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  17. Content type: Research article

    A high prevalence of neutropenia has been reported in several ethnic groups amongst whom many healthy individuals with low neutrophil counts undergo unnecessary investigations. This study aims to ascertain the...

    Authors: Srdjan Denic, Hassib Narchi, Lolowa A. Al Mekaini, Suleiman Al-Hammadi, Omar N. Al Jabri and Abdul-Kader Souid

    Citation: BMC Hematology 2016 16:15

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  18. Content type: Study protocol

    Multiple myeloma is a plasma cell tumour with an annual incidence in the UK of approximately 40–50 per million i.e. about 4500 new cases per annum. The triple combination cyclophosphamide, bortezomib (Velcade®...

    Authors: Sarah Brown, Samantha Hinsley, Mónica Ballesteros, Sue Bourne, Paul McGarry, Debbie Sherratt, Louise Flanagan, Walter Gregory, Jamie Cavenagh, Roger Owen, Cathy Williams, Martin Kaiser, Eric Low and Kwee Yong

    Citation: BMC Hematology 2016 16:14

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  19. Content type: Research article

    This study was undertaken to explore the longitudinal patterns of health-related quality of life (HRQoL) among youth and young adults with Hemophilia A (HA) over a 3-year period. This report presents the basel...

    Authors: J. St-Louis, D. J. Urajnik, F. Ménard, S. Cloutier, R. J. Klaassen, B. Ritchie, G. E. Rivard, M. Warner, V. Blanchette and N. L. Young

    Citation: BMC Hematology 2016 16:13

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  20. Content type: Study protocol

    CC-486 is an oral formulation of the epigenetic modifier azacitidine. In an expanded phase 1 trial, CC-486 demonstrated clinical and biological activity in patients with International Prognostic Scoring System...

    Authors: Guillermo Garcia-Manero, Antonio Almeida, Aristoteles Giagounidis, Uwe Platzbecker, Regina Garcia, Maria Teresa Voso, Stephen R. Larsen, David Valcarcel, Lewis R. Silverman, Barry Skikne and Valeria Santini

    Citation: BMC Hematology 2016 16:12

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  21. Content type: Research article

    Langerhans cells (LC) are bone marrow-derived cells in the skin. The LC donor/recipient chimerism is assumed to influence the incidence and severity of graft-versus-host disease (GVHD) after hematopoietic stem...

    Authors: Sabrina Peters, Christian Junghanss, Anne Knueppel, Hugo Murua Escobar, Catrin Roolf, Gudrun Knuebel, Anett Sekora, Iris Lindner, Ludwig Jonas, Mathias Freund and Sandra Lange

    Citation: BMC Hematology 2016 16:11

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  22. Content type: Research article

    Chronic lymphocytic leukemia (CLL) is a mature B-cell neoplasm characterized by the expansion of CD5-positive lymphocytes in peripheral blood. While CLL is the most common type of leukemia in Western populatio...

    Authors: Abibatou Sall, Awa Oumar Touré, Fatimata Bintou Sall, Moussa Ndour, Seynabou Fall, Abdoulaye Sène, Blaise Félix Faye, Moussa Seck, Macoura Gadji, Tandakha Ndiaye Dièye, Claire Mathiot, Sophie Reynaud, Saliou Diop and Martine Raphaël

    Citation: BMC Hematology 2016 16:10

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