Skip to main content

Advertisement

Articles

Page 4 of 5

  1. The genetic polymorphism of thiopurine methyltransferase (TPMT) is well characterized in most populations. Four common polymorphic alleles are associated with impaired activity of the enzyme. These are TPMT*2 ...

    Authors: Basim Mohammad Ayesh, Wael Mohammad Harb and Abdalla Assaf Abed

    Citation: BMC Blood Disorders 2013 13:3

    Content type: Research article

    Published on:

  2. Sickle cell anaemia (SCA) is a major chronic health problem in Uganda. In patients with SCA, the level of foetal haemoglobin (HbF) has been found to be important in influencing the clinical course of the disea...

    Authors: Lena Mpalampa, Christopher M Ndugwa, Henry Ddungu and Richard Idro

    Citation: BMC Blood Disorders 2012 12:11

    Content type: Research article

    Published on:

  3. In some clinical situations, for which RCT are rare or impossible, the majority of the evidence comes from observational studies, but standard estimations could be biased because they ignore covariates that co...

    Authors: Matthieu Resche-Rigon, Romain Pirracchio, Marie Robin, Regis Peffault De Latour, David Sibon, Lionel Ades, Patricia Ribaud, Jean-Paul Fermand, Catherine Thieblemont, Gérard Socié and Sylvie Chevret

    Citation: BMC Blood Disorders 2012 12:10

    Content type: Technical advance

    Published on:

  4. This case report highlights the relevance of quantifying the BCR-ABL gene in cerebrospinal fluid of patients with suspected relapse of chronic myeloid leukemia in the central nervous system.

    Authors: Mary Fuchs, Mike Reinhöfer, Andreas Ragoschke-Schumm, Herbert G Sayer, Klas Böer, Otto W Witte, Andreas Hochhaus and Hubertus Axer

    Citation: BMC Blood Disorders 2012 12:9

    Content type: Case report

    Published on:

  5. The prevalence of monoclonal gammopathy of undetermined significance (MGUS), a premalignant plasma-cell disorder has not been determined in our geographic area Nigeria.

    Authors: A Lawretta Onwah, Titilope A Adeyemo, Adewumi Adediran, Sarah O Ajibola and Alani S Akanmu

    Citation: BMC Blood Disorders 2012 12:7

    Content type: Research article

    Published on:

  6. Thalassemia is a common disorder worldwide with a predominant incidence in Mediterranean countries, North Africa, the Middle East, India, Central Asia, and Southeast Asia. Whilst substantial progress has been ...

    Authors: Giovanni Caocci, Fabio Efficace, Francesca Ciotti, Maria Grazia Roncarolo, Adriana Vacca, Eugenia Piras, Roberto Littera, Raji Suleiman Dawood Markous, Gary Stephen Collins, Fabio Ciceri, Franco Mandelli, Sarah Marktel and Giorgio La Nasa

    Citation: BMC Blood Disorders 2012 12:6

    Content type: Research article

    Published on:

  7. Although G6PD deficiency is the most common genetically determined blood disorder among Iraqis, its molecular basis has only recently been studied among the Kurds in North Iraq, while studies focusing on Arabs...

    Authors: Bassam MS Al-Musawi, Nasir Al-Allawi, Ban A Abdul-Majeed, Adil A Eissa, Jaladet MS Jubrael and Hanan Hamamy

    Citation: BMC Blood Disorders 2012 12:4

    Content type: Research article

    Published on:

  8. Hemoglobin E is an important hemoglobin variant with a worldwide distribution. A number of hemoglobinopathies have been reported from Pakistan. However a comprehensive description of hemoglobin E syndromes for...

    Authors: Bushra Moiz, Mashhooda Rasool Hashmi, Amna Nasir, Anila Rashid and Tariq Moatter

    Citation: BMC Blood Disorders 2012 12:3

    Content type: Research article

    Published on:

  9. Chronic immune thrombocytopenia (ITP) is a debilitating autoimmune disorder that causes a reduction in blood platelets and increased risk of bleeding. ITP is currently managed with various pharmacologic therap...

    Authors: T Michelle Brown, Ruslan V Horblyuk, Kelly M Grotzinger, Axel C Matzdorff and Chris L Pashos

    Citation: BMC Blood Disorders 2012 12:2

    Content type: Research article

    Published on:

  10. We report a patient with cytogenetically confirmed Fanconi anaemia with associated diffuse bilateral pulmonary arterio-venous fistulae. This is only the second reported case of diffuse pulmonary arterio-venous...

    Authors: Lasitha Samarakoon, Nuwan Ranawaka, Chaturaka Rodrigo, Godwin R Constantine and Lalindra Goonarathne

    Citation: BMC Blood Disorders 2012 12:1

    Content type: Case report

    Published on:

  11. Recommendations given for intravenous iron treatment are typically not supported by a high level of evidence. This meta-analysis addressed this by summarising the available date from clinical trials of ferric ...

    Authors: R Andrew Moore, Helen Gaskell, Peter Rose and Jonathan Allan

    Citation: BMC Blood Disorders 2011 11:4

    Content type: Research article

    Published on:

  12. Dyskeratosis congenita (DC) is a progressive, multi-system, inherited disorder of telomere biology with high risks of morbidity and mortality from bone marrow failure, hematologic malignancy, solid tumors and ...

    Authors: Neelam Giri, Rees Lee, Albert Faro, Charles B Huddleston, Frances V White, Blanche P Alter and Sharon A Savage

    Citation: BMC Blood Disorders 2011 11:3

    Content type: Case report

    Published on:

  13. Several studies have shown that the pathophysiology of homozygous sickle cell anaemia (SCA) results in a myriad of metabolic, nutritional, haematological and clinical effects that interact with other co-morbid...

    Authors: Bamidele A Iwalokun, Senapon O Iwalokun, Semande O Hodonu, Ayoola O Aina and Phillip U Agomo

    Citation: BMC Blood Disorders 2011 11:2

    Content type: Research article

    Published on:

  14. Interpreting the erythroid lineage in populations with high frequency of α+ thalassemia allele is challenging due to the high prevalence of α+ thalassemia homozygotes. For such populations, separate reference val...

    Authors: Srdjan Denic, Abdul-Kader Souid, Nicolaas Nagelkerke, Saad Showqi and Ghazala Balhaj

    Citation: BMC Blood Disorders 2011 11:1

    Content type: Research article

    Published on:

  15. There are many descriptions of the association of pica with iron deficiency in adults, but there are few reports in which observations available at diagnosis of iron deficiency were analyzed using multivariabl...

    Authors: James C Barton, J Clayborn Barton and Luigi F Bertoli

    Citation: BMC Hematology 2010 10:9

    Content type: Research article

    Published on:

  16. Chronic Myeloid Leukemia (CML) is caused by the abnormal fusion protein BCR-ABL1, a constitutively active tyrosine kinase and product of the Philadelphia chromosome. Gleevec (Imatinib mesylate) is a selective ...

    Authors: Gyan K Kayastha, Padma Gurung, Paras K Acharya, Buddhi P Paudyal, Bruce Hayes, Mark Zimmerman, Arjun Karki and Aaron S Mansfield

    Citation: BMC Hematology 2010 10:8

    Content type: Research article

    Published on:

  17. The monitoring of BCR-ABL transcript levels by real-time quantitative polymerase chain reaction (RT-qPCR) has become important to assess minimal residual disease (MRD) and standard of care in the treatment of chr...

    Authors: Mariana Serpa, Sabri S Sanabani, Pedro Enrique Dorliac-Llacer, Monika Conchon, Thales Dalessandro Meneguin Pereira, Luciana Nardinelli, Juliana Lima Costa, Mafalda Megumi Yoshinaga Novaes, Patricia de Barros Ferreira and Israel Bendit

    Citation: BMC Hematology 2010 10:7

    Content type: Research article

    Published on:

  18. Glucose-6-Phosphate dehydrogenase (G6PD) is a key enzyme of the pentose monophosphate pathway, and its deficiency is the most common inherited enzymopathy worldwide. G6PD deficiency is common among Iraqis, inc...

    Authors: Nasir Al-Allawi, Adil A Eissa, Jaladet MS Jubrael, Shakir AR Jamal and Hanan Hamamy

    Citation: BMC Hematology 2010 10:6

    Content type: Research article

    Published on:

  19. The first survey on sickle cell disease (SCD) done in Uganda in 1949, reported the district of Bundibugyo in Western Uganda to have the highest sickle cell trait (SCT) prevalence (45%). This is believed to be ...

    Authors: Andrew L Okwi, Wilson Byarugaba, Christopher M Ndugwa, Arthur Parkes, Michael Ocaido and James K Tumwine

    Citation: BMC Hematology 2010 10:5

    Content type: Research article

    Published on:

  20. Reference ranges are available for different blood cell counts. These ranges treat each cell type independently and do not consider possible correlations between cell types.

    Authors: Rowan McIlhagger, Alan J Gow, Caroline E Brett, Janie Corley, Michelle Taylor, Ian J Deary and John M Starr

    Citation: BMC Hematology 2010 10:4

    Content type: Research article

    Published on:

  21. In 2004, wheat flour fortification (WFF) with iron was implemented in Kazakhstan as a public health strategy to increase the iron intake of all women of childbearing age and of children. In 2003, before starti...

    Authors: Ainur Baizhumanova, Akio Nishimura, Katsuki Ito, Junichi Sakamoto, Nailya Karsybekova, Igor Tsoi and Nobuyuki Hamajima

    Citation: BMC Hematology 2010 10:2

    Content type: Research article

    Published on:

  22. Knowledge of the factors associated with health-related quality of life (HRQOL) among patients with thalassemia is essential in developing more suitable clinical, counseling, and social support programs to imp...

    Authors: Montarat Thavorncharoensap, Kitti Torcharus, Issarang Nuchprayoon, Arthorn Riewpaiboon, Kaemthong Indaratna and Bang-on Ubol

    Citation: BMC Hematology 2010 10:1

    Content type: Research article

    Published on:

  23. We studied the application of the BCR-ABL1 + 9q34 tri-colour dual fusion fluorescence in situ hybridization (FISH) system in the characterization of fusion signal pattern and the monitoring of residual disease in...

    Authors: Lisa LP Siu, Edmond SK Ma, Wai Shan Wong, Man Hong Chan and Kit Fai Wong

    Citation: BMC Hematology 2009 9:4

    Content type: Research article

    Published on:

  24. Benign neutropenia, i.e., neutropenia not associated with an increased risk of infection, may result in serious medical consequences when a 'standard' definition of neutropenia (absolute neutrophil count (ANC)...

    Authors: Srdjan Denic, Saad Showqi, Christoph Klein, Mohamed Takala, Nicollas Nagelkerke and Mukesh M Agarwal

    Citation: BMC Hematology 2009 9:3

    Content type: Research article

    Published on:

  25. Sickle cell disease is the most frequent hereditary disease in Brazil, and people with the disease may be hospitalised several times in the course of their lives. The purpose of this study was to estimate the ...

    Authors: Monique Morgado Loureiro, Suely Rozenfeld, Marilia Sá Carvalho and Rodrigo Doyle Portugal

    Citation: BMC Hematology 2009 9:2

    Content type: Research article

    Published on:

  26. Primary eosinophlia associated with the FIP1L1-PDGFRA rearrangement represents a subset of chronic eosinophilic leukaemia (CEL) and affected patients are very sensitive to imatinib treatment. This study was under...

    Authors: Gedeon Loules, Fani Kalala, Nikolaos Giannakoulas, Emmanouil Papadakis, Panagiota Matsouka and Matthaios Speletas

    Citation: BMC Hematology 2009 9:1

    Content type: Research article

    Published on:

  27. Although it is widely appreciated that vigorous physical activity can increase the risk of bleeding episodes in children with haemophilia, the magnitude of the increase in risk is not known. Accurate risk esti...

    Authors: Carolyn R Broderick, Robert D Herbert, Jane Latimer, Chris Barnes, Julie A Curtin and Paul Monagle

    Citation: BMC Hematology 2008 8:2

    Content type: Study protocol

    Published on:

  28. Influenza vaccines are recommended for administration by the intramuscular route. However, many physicians use the subcutaneous route for patients receiving an oral anticoagulant because this route is thought ...

    Authors: Josep Casajuana, Begoña Iglesias, Mireia Fàbregas, Francesc Fina, Joan-Antoni Vallès, Rosa Aragonès, Mència Benítez and Edurne Zabaleta

    Citation: BMC Hematology 2008 8:1

    Content type: Research article

    Published on:

  29. The purpose of this study was to evaluate the impact of recombinant human erythropoietin (rHuEPO) use for anemia of critical illness at a practice site where delayed initiation is common.

    Authors: Jeremiah J Duby, Brian L Erstad, Jacob Abarca, James M Camamo, Yvonne Huckleberry and Stuart N Bramblett

    Citation: BMC Hematology 2007 7:1

    Content type: Research article

    Published on:

  30. Warfarin is a coumarin anti-coagulant, used widely for the therapeutic and prophylactic anticoagulation. Although, it is considered as a life saving medicine, it is associated with the significant adverse effe...

    Authors: Jayesh Sagar, Vikas Kumar, Dharmendra K Shah and Ashok Bhatnagar

    Citation: BMC Hematology 2006 6:7

    Content type: Case report

    Published on:

  31. Thrombosis is the fatal and disabling consequence of cardiovascular diseases, the leading cause of mortality and morbidity in Western countries. Two inbred mouse strains, C57BL/6J and A/J, have marked differen...

    Authors: Jane Hoover-Plow, Aleksey Shchurin, Erika Hart, Jingfeng Sha, Annie E Hill, Jonathan B Singer and Joseph H Nadeau

    Citation: BMC Hematology 2006 6:6

    Content type: Research article

    Published on:

  32. In the context of sickle cell anemia, peripheral blood indexes provide key information that is also potentially influenced by age. Therefore, it is necessary to understand the extent and nature of interactions...

    Authors: Mamta Sharma, Manju R Mamtani, Manik Amin, Tushar P Thakre, Smita Sharma, Amit Amin and Hemant Kulkarni

    Citation: BMC Hematology 2006 6:3

    Content type: Research article

    Published on:

  33. Children with haemophilia have lower levels of fitness and strength than their healthy peers. We present the protocol of a study designed to determine whether an exercise intervention improves quality of life,...

    Authors: Carolyn R Broderick, Robert D Herbert, Jane Latimer, Julie A Curtin and Hiran C Selvadurai

    Citation: BMC Hematology 2006 6:2

    Content type: Study protocol

    Published on:

  34. We have previously demonstrated that therapy with orally administered L-glutamine improves nicotinamide adenosine dinucleotide (NAD) redox potential of sickle red blood cells (RBC). On further analysis of L-gl...

    Authors: Yutaka Niihara, Neil M Matsui, Yamin M Shen, Dean A Akiyama, Cage S Johnson, M Alenor Sunga, John Magpayo, Stephen H Embury, Vijay K Kalra, Seong Ho Cho and Kouichi R Tanaka

    Citation: BMC Hematology 2005 5:4

    Content type: Research article

    Published on:

  35. Rotational thromboelastography (ROTEG) has been proposed as a monitoring tool that can be used to monitor treatment of hemophilia with recombinant factor VIIa (rFVIIa). In these studies special non-standard re...

    Authors: Martin Engström, Peter Reinstrup and Ulf Schött

    Citation: BMC Hematology 2005 5:3

    Content type: Research article

    Published on:

  36. With chronic infection, hepatitis C virus (HCV) RNA can be detected in B cells and associated with B-cell disorders, but these are not well defined.

    Authors: Mingdong Zhang, Thomas R O'Brien, William C Kopp and James J Goedert

    Citation: BMC Hematology 2005 5:2

    Content type: Research article

    Published on:

  37. Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is performed mainly in patients with high-risk or advanced hematologic malignancies and congenital or acquired aplastic anemias. In the context of...

    Authors: Justyna Jółkowska, Anna Pieczonka, Tomasz Strabel, Dariusz Boruczkowski, Jacek Wachowiak, Peter Bader and Michał Witt

    Citation: BMC Hematology 2005 5:1

    Content type: Research article

    Published on:

  38. Drug-induced agranulocytosis, a severe side effect marked by a deficit or absolute lack of granulocytic white blood cells, is a rare side-effect of the anti-inflammatory drug sulphasalazine. Mutations in the h...

    Authors: Annica Jacobson, Håkan Melhus and Mia Wadelius

    Citation: BMC Hematology 2004 4:5

    Content type: Research article

    Published on:

  39. In view of clinical observations and laboratory results that support a central role of the spleen in idiopathic thrombocytopenic purpura (ITP) pathophysiology, we studied the effect of splenectomy on type-1 an...

    Authors: Fotios P Panitsas and Athanasia Mouzaki

    Citation: BMC Hematology 2004 4:4

    Content type: Case report

    Published on:

2017 Journal Metrics

Advertisement