Gale RP, Butturini A: Maintenance chemotherapy and cure of childhood acute lymphoblastic leukaemia. Lancet. 1991, 338 (8778): 1315-1318. 10.1016/0140-6736(91)92604-Z.
Article
CAS
PubMed
Google Scholar
Lennard L: The clinical pharmacology of 6-mercaptopurine. Eur J Clin Pharmacol. 1992, 43 (4): 329-339. 10.1007/BF02220605.
Article
CAS
PubMed
Google Scholar
Adam de Beaumais T, Jacqz-Aigrain E: Pharmacogenetic determinants of mercaptopurine disposition in children with acute lymphoblastic leukemia. Eur J Clin Pharmacol. 2012, 68 (9): 1233-1242. 10.1007/s00228-012-1251-4.
Article
CAS
PubMed
Google Scholar
Evans WE, Hon YY, Bomgaars L, Coutre S, Holdsworth M, Janco R, Kalwinsky D, Keller F, Khatib Z, Margolin J, Murray J, Quinn J, Ravindranath Y, Ritchey K, Roberts W, Rogers ZR, Schiff D, Steuber C, Tucci F, Kornegay N, Krynetski EY, Relling MV: Preponderance of thiopurine S-methyltransferase deficiency and heterozygosity among patients intolerant to mercaptopurine or azathioprine. J Clin Oncol. 2001, 19 (8): 2293-2301.
CAS
PubMed
Google Scholar
Ujiie S, Sasaki T, Mizugaki M, Ishikawa M, Hiratsuka M: Functional characterization of 23 allelic variants of thiopurine S-methyltransferase gene (TPMT*2 - *24). Pharmacogenet Genomics. 2008, 18 (10): 887-893. 10.1097/FPC.0b013e3283097328.
Article
CAS
PubMed
Google Scholar
Yates CR, Krynetski EY, Loennechen T, Fessing MY, Tai HL, Pui CH, Relling MV, Evans WE: Molecular diagnosis of thiopurine S-methyltransferase deficiency: genetic basis for azathioprine and mercaptopurine intolerance. Ann Intern Med. 1997, 126 (8): 608-614.
Article
CAS
PubMed
Google Scholar
Krynetski EY, Tai HL, Yates CR, Fessing MY, Loennechen T, Schuetz JD, Relling MV, Evans WE: Genetic polymorphism of thiopurine methyltransferase: clinical importance and molecular mechanisms. Pharmacogenetics. 1996, 6 (4): 279-290. 10.1097/00008571-199608000-00001.
Article
CAS
PubMed
Google Scholar
McLeod HL, Lin JS, Scott EP, Pui C-H, Evans WE: Thiopurine methyltransferase activity in American white subjects and black subjects. Clin Pharmacol Ther. 1994, 55 (1): 15-20. 10.1038/clpt.1994.4.
Article
CAS
PubMed
Google Scholar
Chrzanowska M, Kuehn M, Januszkiewicz-Lewandowska D, Kurzawski M, Droździk M: Thiopurine S-methyltransferase phenotype-genotype correlation in children with acute lymphoblastic leukemia. Acta Pol Pharm. 2012, 69 (3): 405-410.
CAS
PubMed
Google Scholar
Szumlanski C, Otterness D, Her C, Lee D, Brandriff B, Kelsell D, Spurr N, Lennard L, Wieben E, Weinshilboum R: Thiopurine methyltransferase pharmacogenetics: human gene cloning and characterisation of a common polymorphism. DNA Cell Biol. 1996, 15 (1): 17-30. 10.1089/dna.1996.15.17.
Article
CAS
PubMed
Google Scholar
World Medical Association Declaration of Helsinki: Ethical principles for medical research involving human subjects. http://www.wma.net/en/30publications/10policies/b3/index.html,
Zhang JP, Guan Y, Wu JH, Xu AL, Zhou S, Huang M: Phenotyping and genotyping study of thiopurine S-methyltransferase in healthy Chinese children: A comparison of Han and Yao ethnic groups. Br J Clin Pharmacol. 2004, 58 (2): 163-168. 10.1111/j.1365-2125.2004.02113.x.
Article
CAS
PubMed
PubMed Central
Google Scholar
Hindorf U, Appell ML: Genotyping should be considered the primary choice for pre-treatment evaluation of thiopurine methyltransferase function. J Crohns Colitis. 2012, 6 (6): 655-659. 10.1016/j.crohns.2011.11.014.
Article
PubMed
Google Scholar
Peregud-Pogorzelski J, Tetera-Rudnicka E, Kurzawski M, Brodkiewicz A, Adrianowska N, Mlynarski W, Januszkiewicz D, Drozdzik M: Thiopurine S-methyltransferase (TPMT) polymorphisms in children with acute lymphoblastic leukemia, and the need for reduction or cessation of 6-mercaptopurine doses during maintenance therapy: the Polish multicenter analysis. Pediatr Blood Cancer. 2011, 57 (4): 578-582. 10.1002/pbc.23013.
Article
PubMed
Google Scholar
Higgs JE, Payne K, Roberts C, Newman WG: Are patients with intermediate TPMT activity at increased risk of myelosuppression when taking thiopurine medications?. Pharmacogenomics. 2010, 11 (2): 177-188. 10.2217/pgs.09.155.
Article
CAS
PubMed
Google Scholar
Efrati E, Adler L, Krivoy N, Sprecher E: Distribution of TPMT risk alleles for thioupurine toxicity in the Israeli population. Eur J Clin Pharmacol. 2009, 65 (3): 257-262. 10.1007/s00228-008-0590-7.
Article
CAS
PubMed
Google Scholar
Hakooz N, Arafat T, Payne D, Ollier W, Pushpakom S, Andrews J, Newman W: Genetic analysis of thiopurine methyltransferase polymorphism in the Jordanian population. Eur J Clin Pharmacol. 2010, 66 (10): 999-1003. 10.1007/s00228-010-0826-1.
Article
CAS
PubMed
Google Scholar
Tumer TB, Ulusoy G, Adali O, Sahin G, Gozdasoglu S, Arinc E: The low frequency of defective TPMT alleles in Turkish population: a study on pediatric patients with acute lymphoblastic leukemia. Am J Hematol. 2007, 82 (10): 906-910. 10.1002/ajh.20947.
Article
CAS
PubMed
Google Scholar
Azad M, Kaviani S, Soleimani M, Noruzinia M, Hajfathali A: Common Polymorphism’s Analysis of Thiopurine S-Methyltransferase (TPMT) in Iranian Population. Yakhteh Med J. 2009, 11 (3): 311-316.
CAS
Google Scholar
Marra C, Esdaile JM, Anis AH: Practical pharmacogenetics: The cost effectiveness of screening for thiopurine methyltransferase polymorphism in patients with rheumatological conditions treated with azathioprine. J Rheumatol. 2002, 29 (12): 2507-2512.
PubMed
Google Scholar
Fakhoury M, Andreu-Gallien J, Mahr A, Medard Y, Azougagh S, Vilmer E, Jacqz-Aigrain E: Should TPMT genotype and activity be used to monitor 6-mercaptopurine treatment in children with acute lymphoblastic leukaemia?. J Clin Pharm Ther. 2007, 32 (6): 633-639. 10.1111/j.1365-2710.2007.00858.x.
Article
CAS
PubMed
Google Scholar