Table 1 Frequencies of TPMT alleles in 56 samples of Gaza pediatric patient with ALL
Allele | SNP | Amino acid substitution | Allelic count | Allelic frequency % |
|---|---|---|---|---|
TPMT*1 | Wild-Type | - | 111 | 99.11 |
TPMT*2 | c.238G>C | Ala>Pro | 0 | 0 |
TPMT*3A | c.460G>A, c.719A>G | Ala>Thr, Tyr> Cys | 1 | 0.89 |
TPMT*3B | c.460G>A | Ala>Thr | 0 | 0 |
TPMT*3C | c.719A>G | Tyr> Cys | 0 | 0 |
Total | - | - | 112 | 100 |