Table 5 Disease factors and physical HRQoL of adolescents with SCD at multivariate regression analysis (adolescents and caretakers report)
Variables | Physical HRQoL | |||
|---|---|---|---|---|
Adolescents’ response Estimate (95% CI) | P | Caretakers’ response Estimate (95% CI) | p | |
Malaria | ||||
No | 1.00 | 100 | ||
Yes | 32.39(20.14,44.63) | < 0.001 | 37.05(27.95,4.14) | < 0.001 |
Hydroxyurea | ||||
No | 1.00 | 1.00 | ||
Yes | −0.84(−10.98,9.29) | 0.869 | 5.30(−5.59,16.20) | 0.336 |
Folic acid | ||||
No | 1.00 | 1.00 | ||
Yes | −28.76(− 45.41,-12.10) | 0.001 | − 46.17(− 65.96,-26.39) | < 0.001 |
Pneumococcal vaccine | ||||
No | 1.00 | 1.00 | ||
Yes | 28.43(16.78,40.09) | < 0.001 | 31.37(22.22,40.51) | < 0.001 |
Pain | ||||
No | 1.00 | 1.00 | ||
Yes | −4.70(− 14.35,4.95) | 0.336 | − 10.02(− 19.22,-0.81) | 0.033 |
Fever | ||||
No | 1.00 | 1.00 | ||
Yes | 24.39(15.03,33.74) | < 0.001 | 30.67(23.5,37.84) | < 0.001 |
Stroke | ||||
No | 1.00 | 1.00 | ||
Yes | 9.15(−0.75,19.05) | 0.070 | −29.34(−40.69,18.59) | < 0.001 |
Blood transfusion | ||||
None | 1.00 | 1.00 | ||
1–3 | 6.63(−6.60,19.86) | 0.323 | 3.48(−8.40,15.36) | 0.562 |
> 3 | 31.17(11.6.2,50.72) | 0.002 | 24.03(8.83,39.23) | 0.002 |