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Table 2 Mean (±sd) hematological parameter values of omega-3 fatty acid treated, hydroxyurea treated and untreated patients (HbSS) and healthy controls

From: Coagulation profile of Sudanese children with homozygous sickle cell disease and the effect of treatment with omega-3 fatty acid on the coagulation parameters

 

Omega-3 FA Treated Patients

Untreated patients

HU Treated

Healthy Controls

Hb (g/l)

75.6 ± 16.2***

75.9 ± 10.3+++

79.5 ± 10.3

126.0 ± 10.9

HCt

22.9 ± 4.7***

22.9 ± 3.0+++

23.8 ± 2.8

38.0 ± 3.5

RBC

2.8 ± 0.7***

2.7 ± 0.5+++

2.8 ± 0.6

4.6 ± 0.5

MCV (fl)

84.3 ± 8.6

86.5 ± 7.1

87.8 ± 11.6

82.3 ± 4.7

MCH (pg)

27.9 ± 3.4

28.6 ± 3.0

29.5 ± 4.4

27.6 ± 1.9

MCHC

33.3 ± 2.0

33.1 ± 1.4

33.4 ± 0.9

33.5 ± 1.5

PLT

489.5 ± 121.1***

533.6 ± 98.7+++

414.5 ± 109.9×

330.3 ± 72.5

WBC

12.4 ± 4.3***

13.3 ± 3.4+++

13.6 ± 3.7

6.3 ± 1.3

  1. ***p < 0.001 Omega 3 treated versus healthy controls
  2. ++p < 0.01, +++p < 0.001 Untreated patients versus healthy controls
  3. x p < 0.05, HU treated versus untreated patients