Table 3 Distribution of the median (25th – 75th) hematological data among the βS globin haplotypes and -α3.7Kb-thalassemia
βS globin Haplotype | -α3.7Kb-Thalassemia | ||||||
|---|---|---|---|---|---|---|---|
HbSC (N = 52) | SCA (N = 99) | HbSC (N = 52) | SCA (N = 99) | ||||
Median (25th – 75th) | Median (25th – 75th) | Median (25th – 75th) | Median (25th – 75th) | Median (25th – 75th) | Median (25th – 75th) | Median (25th – 75th) | Median (25th – 75th) |
Absence CAR N = 26 | Presence CAR N = 26 | Absence CAR N = 29 | Presence CAR N = 70 | Absence -α3.7Kb N = 43 | Presence -α3.7Kb N = 9 | Absence -α3.7Kb N = 85 | Presence -α3.7Kb N = 14 |
HbS | HbS | Hb | Hb | ||||
50.0 (48.1–51.4) | 50.6 (49.5–51.6) | 83.0 (76.0–88.3) | 88.3 (83.5–91.7) | 10.8 (10.1–11.6) | 10.9 (9.9–12.4) | 7.6 (7.1–8.3) | 8.2 (7.3–8.8) |
p = 0.301 | p = 0.004 | p = 0.735 | p = 0.427 | ||||
HbF | HbF | Ht | Ht | ||||
1.9 (0.8–4.5) | 1.3 (0.7–3.2) | 12.9 (7.5–18.3) | 7.7 (4.1–11.5) | 30.7 (28.7–32.5) | 31.7 (28.0–34.1) | 21.7 (19.9–24.1) | 23.8 (21.4–25.5) |
p = 0.181 | p = 0.005 | p = 0.961 | p = 0.252 | ||||
MCV | MCV | ||||||
76.1 (71.5–80.1) | 71.6 (67.3–72.4) | 88.0 (83.6–93.2) | 80.3 (76.3–83.1) | ||||
p = 0.018 | p < 0.001 | ||||||
MCH | MCH | ||||||
27.2 (24.6–28.8) | 25.0 (23.4–26.5) | 30.8 (28.8–32.7) | 27.7 (25.7–29.0) | ||||
p = 0.071 | p < 0.001 | ||||||