Table 1 Summary of coagulation tests
From: A novel fibrinogen mutation: FGA g. 3057 C > T (p. Arg104 > Cys) impairs fibrinogen secretion
Proband | Father | Reference values | |
|---|---|---|---|
TT (s) | 18.6 | 30.8 | 16–18 |
PT (s) | 15.8 | 54.6 | 13–15 |
aPTT (s) | 34.6 | 42.2 | 27–34 |
Fibrinogen (Clauss) | 163 | 122 | |
(mg/dl) | 151 | 200–400 | |
158 | |||
Fibrinogen antigen (mg/dl) | 177 | 126 | 190–400 |
Factor V (%) | 79 | – | 60–140 |
Factor II (%) | 105 | 88 | 60–140 |
Factor VII (%) | 79 | 69 | 65–145 |
Factor X (%) | 82 | 67 | 65–130 |