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Table 3 Abnormal measures of thrombophilia and hypofibrinolysis in 24 women who used hormone replacement therapy on estrogen-progestin oral contraceptives before pulmonary embolism (18 women had coagulation measures)

From: Hospitalization for pulmonary embolism associated with antecedent testosterone or estrogen therapy in patients found to have familial and acquired thrombophilia

 

Factor

V

PTG

Factor VIII

Factor

XI

ACLA

IgG

ACLA

IgM

Lupus anticoagulant

Pro S

Free S

Anti III

Abnormal range

TC/TT

TC/TT

> 150 %

> 150 %

Dated cut pointa

Y

< 63 %

< 66 %

< 80 %

ID# 1

         

78

3

     

20.0

    

4

          

5

TC

      

47

  

6

         

70

8

TC

         

9

      

Y

  

71

10

  

212

       

11

      

Y

   

12

        

61

 

13

    

16.0

  

59

  

14

          

15

  

301

151

 

17.0

  

39

 

17

 

TC

        

18

       

48

  

22

TC

         

24

TC

         
  1. adated cut point for IgG high: ≥ 23 GPL (before 10/31/12); ≥ 15 (after 11/1/12)
  2. dated cut point for IgM high: ≥ 10 MPL (before 4/30/12); ≥ 13 (after 5/1/12)