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Table 2 Abnormal measures of thrombophilia and hypofibrinolysis in 8 men who using testosterone therapy before pulmonary embolism (6 men had coagulation measures)

From: Hospitalization for pulmonary embolism associated with antecedent testosterone or estrogen therapy in patients found to have familial and acquired thrombophilia

 

PTG

MTHFR

PAIG

Homocysteine

Factor VIII

ACLA IgG

Pro C

PRO S

Free S

Abnormal range

TC/TT

TT

4G4G

Dated cut pointa

> 150 %

Dated cut pointb

< 73 %

< 63 %

< 66 %

ID# 1

   

12.0

  

61

  

2

TC

    

18.0

  

57

4

       

64

 

5

  

4G4G

 

223

 

47

49

43

6

 

TT

 

17.3

     

7

   

11.0

     
  1. adated cut point for Homocysteine high: ≥ 15 (11/15/08-12/2/14); ≥ 10.4 (after 12/3/14)
  2. bdated cut point for IgG high: ≥ 23 GPL (before 10/31/12); ≥ 15 (after 11/1/12)