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Table 4 Types of drugs concurrently prescribed with warfarin known to have interaction and their potential effect on INR values (n = 91)

From: Drug-related problems and potential contributing factors in the management of deep vein thrombosis

Drugs

Effect on INR

Severity

Norfloxacin, Metronidazole, Clarithromycin

Increase

Major

Rifampin

Decrease

Major

Isoniazid, Omeprazole, Tramadol, Ceftriaxone, Cimetidine, Allopurinol, Azithromycin

Increase

Moderate

Nevirapine, Neurobion, Mercaptopurine

Decrease

Moderate

Efavirenz, Hydrocortisone, Prednisolone

Increase/Decrease

Moderate

Methotrexate, Vincristine, Furosemide, Simvastatin

Increase

Minor

Hydrochlorothiazide

Decrease

Minor