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Figure 2 | BMC Hematology

Figure 2

From: Application of tri-colour, dual fusion fluorescence in situ hybridization (FISH) system for the characterization of BCR-ABL1 fusion in chronic myelogenous leukaemia (CML) and residual disease monitoring

Figure 2

Representative interphase and metaphase images from the four pattern of signals. The upper panels are probe and reverse DAPI images using the BCR-ABL1 dual colour, dual fusion (D-FISH). The lower panels are probe and the cartoon images using the BCR-ABL1 tri-colour, dual fusion. (A) Group 1: classical 1G1O2F signal pattern using D-FISH. (B) Group 2:ABL1 deletion, 2G1O1F signal pattern using D-FISH. (C) Group 3: BCR deletion, 1G2O1F signal pattern using D-FISH. (D) Group 4: reciprocal ABL1-BCR deletion, 1G1O1F signal pattern using D-FISH.

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