Total blood lymphocyte counts in hemochromatosis probands with HFEC282Y homozygosity: relationship to severity of iron overload and HLA-A and -B alleles and haplotypes

Table 1 Iron measures in hemochromatosis probands with HFE C282Y homozygosity¹

Iron measure	Men (95% CI) [n]	Women (95% CI) [n]	p value
Serum iron, μg/dL	209 (137, 317) [81]	193 (118, 315) [51]	0.0523
Transferrin saturation, %	85 (59, 121) [83]	77 (44, 133) [52]	0.0120
Serum ferritin, ng/mL	1097 (209, 5768) [81]	546 (84, 3535) [56]	<0.0001
Phlebotomy to achieve iron depletion, units	29 (7, 122) [73]	17 (4, 76) [42]	0.0001

¹Serum iron, transferrin saturation, and serum ferritin levels were measured at diagnosis of hemochromatosis. Values were transformed (log_e) to achieve normal distributions; comparisons were made using a student t-test (two-tail). Data displayed in the table are expressed as mean (95% CI) after computing antilogs_e of the transformed data; p values < 0.05 were defined as significant.

ISSN: 2052-1839