Subcutaneous group (n = 115) | Intramuscular group (n = 92) | 95% confidence interval of the difference | |
---|---|---|---|
Mean circumference of the arm (SD), cm, 24 h | 32,1 (3,4) | 32,2 (4,2) | |
Mean change circumference of the arm (SD), cm, 24 h | +0,20 (1,44) | +0,28 (0,91) | -0,40 to +0,25 * |
Patients with increase of the circumference of the arm >= 1 cm, n (%), 24 h | 27 (23,5%) | 18 (19,6%) | -7,3% to +15,1% |
Patients with skin lesions in the administration area, n (%), 24 h | 43 (37,4%) | 16 (17,4%) | +8,2% to +31,8% |
Erythema, n | 36 | 8 | |
Papule, n | 0 | 3 | |
Plaque, n | 7 | 5 | |
Nodule, n | 0 | 2 | |
Cyst, n | 0 | 0 | |
Vesicle, n | 0 | 0 | |
Blister, n | 0 | 0 | |
Ulcer, n | 0 | 0 | |
Scab, n | 0 | 2 | |
Haematoma, n | 2 | 1 | |
Pruritus, n | 4 | 2 | |
Insensitivity, n | 1 | 0 | |
Mean Visual Analog Pain Scale (SD), 24 h | 0,43 (1,08) | 0,29 (0,84) | -0,12 to 0,41 * |
Patients with Visual Analog Pain Scale > 0, n (%), 24 h | 23 (20,0%) | 13 (14,1%) | -4,3% to +16,1% |
Mean INR (SD), 24 h | 2,28 (0,64) | 2,30 (0,70) | |
Mean change INR (SD), 24 h | +0,04 (0,50) | -0,06 (0,55) | -0,04 to +0,25 * |
Mean INR (SD), 10d | 2,31 (0,67) | 2,44 (0,95) | |
Mean change INR (SD), 10d | +0,08 (0,79) | +0,07 (0,93) | -0,24 to +0,24 * |