From: Patient-reported treatment burden of chronic immune thrombocytopenia therapies
Independent variables | Corticosteroids | IVIg | Anti-D | Rituximab | Splenectomy | |||||
---|---|---|---|---|---|---|---|---|---|---|
Group Mean (SD)§§ | 3.73 | (0.70) | 3.56 | (1.00) | 3.60 | (0.95) | 3.46 | (1.03) | 2.74 | (1.09) |
Adjusted R 2 (N) | 0.19 | (440) | 0.11 | (208) | 0.32 | (128) | 0.19 | (130) | 0.12 | (151) |
Age | 0.03(.00) | -0.06(.00) | -0.01(.00) | -0.13(.01) | 0.05(.01) | |||||
Frequency of dry bleeds (0 = No bleeds, 1 = bleeds) | 0.01(.10) | -0.10(.25) | 0.24(.26) | ** | 0.16(.29) | -0.03(.25) | ||||
Time since diagnosis¶ | -0.01 (.05) | 0.00(.12) | -0.01(.13) | 0.07(.17) | 0.13(.26) | |||||
Gender (0 = Male; 1 = Female) | 0.17(.08) | **** | 0.10(.17) | 0.09(.20) | 0.06(.21) | 0.05(.21) | ||||
Longest cycle duration§ | -0.07(.04) | - | - | - | - | |||||
Typical low platelet count (past year) | 0.02(.00) | 00(0) | 0.25(.00) | * | -0.10(.00) | 0.14(.00) | ||||
Need to stop or reduce (0 = No, 1 = Yes) | 0.15(.06) | ** | 0.31(.16) | **** | 0.43(.17) | **** | 0.34(.21) | **** | - | |
Number of treatment effects | 0.35(.01) | **** | 0.15(.04) | * | 0.24(.04) | ** | 0.23(.04) | ** | 0.34(.09) | **** |
Number of ITP treatments (among 5 treatment | -0.04(.02) | -0.11(.05) | -0.04(.06) | 0.09(.07) | -0.01(.07) | |||||
types) | ||||||||||
Other ITP medications in combination (0 = No; | 0.08(.07) | 0.07(.15) | 0.08(.16) | 0.00(.18) | - | |||||
1 = Yes) | ||||||||||
Time since last taking drug/procedure† | 0.08(.07) | -0.02(.15) | -0.18(.19) | * | -0.11(.19) | 0.01(.16) | ||||
Type of physician‡ | -0.06(.09) | -0.03(26) | 0.11(.27) | 0.07(.40) | -0.02(.24) | |||||
Frequency of wet bleeds (0 = No bleeds, 1 = bleeds) | -0.03(.07) | 0.07(.15) | -0.22(.16) | ** | -0.16(.20) | -0.05(.21) |