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Table 4 Mean score of HRQoL, demographic and disease factors as reported by adolescents

From: Health-related quality of life of adolescents with sickle cell disease in sub-Saharan Africa: a cross-sectional study

Variables PhF p EmF p SocF P SchF p PsyF p
Age group(child)
Means (±SD)
 > 12 57.8 ± 20.13 0.9018 67.6 ± 16.36 0.0079 78.7 ± 18.73 0.1258 60.6 ± 14.93 0.3065 68.9 ± 16.31 0.0348
 ≤12 57.3 ± 20.52   58.5 ± 19.58   72.7 ± 22.57   57.4 ± 17.71   62.9 ± 14.37  
Gender (child)
Means (±SD)
 Male 57.7 ± 21.85 0.9094 68.1 ± 21.01 0.0005 80.6 ± 17.58 0.0070 58.3 ± 19.05 0.9433 69.0 ± 16.76 0.0105
 Female 57.3 ± 19.78   56.9 ± 16.22   70.7 ± 23.05   58.5 ± 15.38   62.0 ± 14.77  
Fever Means (±SD)
 No 54.9 ± 13.19 0.2711 65.9 ± 21.23 0.0385 77.4 ± 2.17 0.2770 56.8 ± 14.17 0.4149 66.7 ± 14.87 0.3070
 Yes 58.7 ± 23.23   59.0 ± 17.38   73.1 ± 24.53   59.3 ± 18.19   63.8 ± 16.44  
Pain
 No 61.5 ± 22.3 0.0735 59.21 ± 20.70 0.3073 74.8 ± 22.53 0.9227 65.1 ± 15.18 0.0003 64.8 ± 15.44 0.3771
 Yes 55.1 ± 18.83   62.64 ± 18.01   74.5 ± 21.07   54.6 ± 16.69   63.9 ± 16.19  
Malaria Means (±SD)
 No 57.5 ± 21.1 0.2940 59.7 ± 15.53 < 0.001 73.6 ± 20.84 0.0003 56.6 ± 16.8 < 0.001 63.3 ± 14.21 < 0.001
 Yes 63.7 ± 8.2   88.5 ± 21.92   95.4 ± 8.77   75.4 ± 8.77   86.4 ± 13.16  
Hydroxyurea Means (±SD)
 No 53.6 ± 18.95 < 0.001 59.5 ± 21.56 0.1179 73.0 ± 24.61 0.2394 56.6 ± 17.48 0.1182 63.1 ± 18.15 0.0866
 Yes 69.5 ± 17.86   65.33 ± 15.09   77.6 ± 12.86   61.7 ± 17.29   68.2 ± 11.20  
Folic acid Means (±SD)
 No 71.5 ± 0.17 0.0638 59.3 ± 1.89 0.7564 78.6 ± 9.45 0.6036 62.9 ± 7.56 0.4634 66.9 ± 5.04 0.7127
 Yes 56.9 ± 20.45   61.6 ± 19.65   74.2 ± 22.06   58.0 ± 17.28   64.6 ± 16.39  
Pneumococcal vaccine Means(±SD)
 No 56.7 ± 17.84 0.4348 58.3 ± 20.93 0.0011 72.3 ± 23.91 0.0586 59.0 ± 18.96 0.4628 63.2 ± 17.97 0.0608
 Yes 59.9 ± 20.54   70.3 ± 8.53   80.3 ± 12.07   56.5 ± 9.47   69.03 ± 7.39  
Stroke Means (±SD)
 No 58.5 ± 21.13 0.1401 63.7 ± 17.05 0.0004 76.1 ± 20.47 0.0441 59.3 ± 16.33 0.1207 66.4 ± 14.86 0.0042
 Yes 51.3 ± 13.39   47.8 ± 24.52   65.7 ± 25.83   52.0 ± 19.43   55.5 ± 19.04  
  1. PhF Physical functioning, EmF Emotional functioning, SocF Social functioning, SchF School functioning, PsyF Psychosocial functioning