Table 4 Genetic modifiers of HbF level among TI patients. HbF percentages of all TI patients are compared with samples homozygote and heterozygote for XmnI SNP, α-thalassemia or a combination of both
From: Molecular characterization of β-thalassemia intermedia in the West Bank, Palestine
All samples | XmnI SNP (+/+) | α-thalassemia Heterozygotes | XmnI SNP & α-thalass | |
|---|---|---|---|---|
N | 51 | 3 | 5 | 1 |
HbF % | ||||
Median | 10.4 | 67.5 | 26.6 | 49.1 |
Range (min– max) | 1.7–83.0 | 49.1–83.0 | 1.7–49.1 | – |
Hb g/dL | ||||
Median | 8.3 | 8.6 | 8.7 | 7.1 |
Range (min-Max) | 6.4–13.9 | 7.7–9.8 | 7.1–9.0 | – |