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Table 2 Hematological data and frequency of thalassemia genotypes among Palestinian β-thalassemia intermedia patients

From: Molecular characterization of β-thalassemia intermedia in the West Bank, Palestine

β- thalassemia genotypes N (%) XmnI SNP α- thalassemia Hb g/dL Hb A2% Hb F %
β++
 IVS-I-6 / IVS-I-6 38 (74.5) −/− αα/ αα 8.4 ± 1.1 6.4 ± 1.4 10.2 ± 6.2
 IVS-I-6 / IVS-I-110 1 (1.96) −/− αIVSI(−5nt)α/ αα 8.7 ND ND
 IVS-I-110 / IVS-I-110 3 (5.88) −/− α3.7/ αα
(1:0:0)a
9/11.7/9.5 3.3/3.2/8.5 1.7/6.4/17
 Beta −101/ Beta − 101 1 (1.96) −/− αα/αα 13.9 4.6 7.4
 Subtotal 43 (84.3)      
β+/β°
 IVS-I-6 / Cd37 1 (1.96) −/− αα/ αα 6.9 3.3 6.6
 IVS-I-110 / Cd37 1 (1.96) −/− αα/ αα 6.5 2.5 30.9
 IVS-II-1 / IVS-II -848 1 (1.96) +/− –α3.7/ αα 7.1 3 49.1
 Subtotal 3 (5.88)      
β°/β°
 IVS-II-1 / IVS-II-1 3 (5.88) +/+ αα/ αα 8.7 ± 0.86 2.1 ± 0.23 72.7 ± 7.3
 IVS-I-1 / Cd37 1 (1.96) −/− αIVSI(−5nt)α/ αα 8.7 2.9 46.8
 Subtotal 4 (7.84)      
β+wt
 IVS-I-1 / βwt 1 (1.96) −/− αα/ αααanti3.7 ND 3.8 6.3
 Total 51 (100)      
  1. ND not determined
  2. aThe numbers (1:0:0) are used to emphasize that only one patient (referred to as 1) has the α3.7/ αα genotype and his hematological values are placed at first position, respectively