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Table 2 Serum Ferritin level-based characteristics of SCA children

From: Magnitude of elevated iron stores and risk associated in steady state sickle cell anemia Congolese children: a cross sectional study

 

Serum ferritin

p

<  500 ng/ml (n = 55)

≥ 500 ng/ml (n = 15)

 

male, %

31(57)

8(53)

0.976*

Age < 5 years, %

10(18)

5(33)

0.286*

HU, %

26(48)

10(67)

0.247*

Major VOC ≥ 2/an, %

6(11)

3(20)

0.391*

Transfusions > 3/year, %

24(44)

11(73)

0.078*

Hct, %

22.4 (20.7–24.8)

22.4 (19.0–28.1)

0.903

Platelets ×103 /mm3

387 (293–472)

288 (172–427)

0.239

WBC, ×103 élts/mm3

11.5 (8.4–14.6)

9.9 (7.2–17.6)

0.951

Reticulocytes, %

11.9 (8.0–17.0)

13.0 (9.5–23.3)

0.964

CRP, mg/l

3.4 (2.0–4.8)

3.8 (2.3–8.5)

0.764

CRP ≥ 6 mg/l, %

7(13)

4(29)

0.233*

CRP ≥ 12 mg/l, %

3(5)

2(13)

0.290*

Indirect Bilirubin, mg/dl

1.9 (1.0–3.6)

1.3 (0.9–2.0)

0.547

LDH, UI/l

568 (424–771)

488 (320–782)

0.559

Free plasma Hb, mg/l

183 (123–282)

130 (107–205)

0.479

Serum iron, μmol/l

16.1 (12.4–19.5)

16.8 (14.9–19.9)

0.849

  1. Record values expressed as frequency or median (IQ 25–75)
  2. Abbreviations: Hct: hematocrit, WB: white blood cells, CRP: Creactive protein, LDH: Lactate dehydrogenase, Hb: hemoglobin, HU: hydroxyurea, VOC: vaso-occlusive crisis
  3. *Fisher Exact test