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Table 6 ANOVA analysis of inter-donor category biochemical and haemolytic parameters

From: Storage related haematological and biochemical changes in Plasmodium falciparum infected and sickle cell trait donor blood

Parameters Sickle cell/malaria negative donors Mean ± SD Sickle cell trait donors Mean ± SD Asymptomatic malaria donors Mean ± SD F P-value
Baseline
 Plasma Hb 0.00 0.00 0.00   
 % haemolysis 0.00 0.00 0.00   
 LDH (U/L) 202.45 ± 20.51 202.90 ± 18.91 173.20 ± 63.74 1.76 0.188
 Potassium (mmol/L) 4.15 ± 0.70 4.22 ± 0.71 4.01 ± 1.50 0.39 0.681
 Sodium (mmol/L) 138.44 ± 2.40 139.52 ± 2.54 126.37 ± 44.53 3.16 0.057
 Chloride (mmol/L) 98.78 ± 1.66 99.88 ± 1.78 90.37 ± 31.87 2.68 0.085
Week 1
 Plasma Hb 0.10 ± 0.00 0.25 ± 0.13 0.20 ± 0.09 23.6 0.001*
 % haemolysis 0.51 ± 0.05 1.12 ± 0.27 1.01 ± 0.35 20.7 0.001*
 LDH (U/L) 318.36 ± 29.30 346.00 ± 78.68 370.90 ± 137.89 14.6 0.001*
 Potassium (mmol/L) 5.54 ± 0.41 7.02 ± 1.15 8.46 ± 0.75 33.6 0.001*
 Sodium (mmol/L) 134.90 ± 3.06 136.95 ± 2.88 121.09 ± 42.80 1.16 0.326
 Chloride (mmol/L) 89.60 ± 3.12 90.53 ± 4.19 81.74 ± 28.74 1.47 0.246
Week 3
 Plasma Hb 0.11 ± 0.03 0.39 ± 0.12 0.23 ± 0.11 22.2 0.001*
 % haemolysis 0.76 ± 0.35 2.21 ± 0.62 1.37 ± 0.41 17.3 0.001*
 LDH (U/L) 436.36 ± 46.31 491.10 ± 47.17 605.77 ± 61.98 33.0 0.001*
 Potassium (mmol/L) 8.05 ± 1.39 12.02 ± 1.61 11.83 ± 1.47 40.3 0.001*
 Sodium (mmol/L) 130.88 ± 4.23 133.45 ± 3.42 129.00 ± 3.51 3.74 0.035
 Chloride (mmol/L) 85.61 ± 3.91 83.37 ± 3.44 85.37 ± 2.85 0.73 0.487
Week 5
 Plasma Hb 0.20 ± 0.04 0.48 ± 0.19 0.28 ± 0.14 8.84 0.001*
 % haemolysis 1.46 ± 0.51 2.75 ± 1.00 1.78 ± 0.65 4.48 0.001*
 LDH (U/L) 536.09 ± 58.71 631.90 ± 109.29 798.00 ± 64.38 13.0 0.001*
 Potassium (mmol/L) 11.35 ± 4.46 19.48 ± 2.86 15.18 ± 1.98 8.25 0.001*
 Sodium (mmol/L) 127.64 ± 6.00 129.62 ± 5.17 124.73 ± 4.79 9.70 0.001*
 Chloride (mmol/L) 84.27 ± 4.29 77.81 ± 4.31 78.61 ± 3.44 1.22 0.309
  1. Abbreviations: LDH = Lactate dehydrogenase, SD = Standard deviation, Hb = Haemoglobin
  2. *p-values less than 0.001