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Table 6 ANOVA analysis of inter-donor category biochemical and haemolytic parameters

From: Storage related haematological and biochemical changes in Plasmodium falciparum infected and sickle cell trait donor blood

Parameters

Sickle cell/malaria negative donors Mean ± SD

Sickle cell trait donors Mean ± SD

Asymptomatic malaria donors Mean ± SD

F

P-value

Baseline

 Plasma Hb

0.00

0.00

0.00

  

 % haemolysis

0.00

0.00

0.00

  

 LDH (U/L)

202.45 ± 20.51

202.90 ± 18.91

173.20 ± 63.74

1.76

0.188

 Potassium (mmol/L)

4.15 ± 0.70

4.22 ± 0.71

4.01 ± 1.50

0.39

0.681

 Sodium (mmol/L)

138.44 ± 2.40

139.52 ± 2.54

126.37 ± 44.53

3.16

0.057

 Chloride (mmol/L)

98.78 ± 1.66

99.88 ± 1.78

90.37 ± 31.87

2.68

0.085

Week 1

 Plasma Hb

0.10 ± 0.00

0.25 ± 0.13

0.20 ± 0.09

23.6

0.001*

 % haemolysis

0.51 ± 0.05

1.12 ± 0.27

1.01 ± 0.35

20.7

0.001*

 LDH (U/L)

318.36 ± 29.30

346.00 ± 78.68

370.90 ± 137.89

14.6

0.001*

 Potassium (mmol/L)

5.54 ± 0.41

7.02 ± 1.15

8.46 ± 0.75

33.6

0.001*

 Sodium (mmol/L)

134.90 ± 3.06

136.95 ± 2.88

121.09 ± 42.80

1.16

0.326

 Chloride (mmol/L)

89.60 ± 3.12

90.53 ± 4.19

81.74 ± 28.74

1.47

0.246

Week 3

 Plasma Hb

0.11 ± 0.03

0.39 ± 0.12

0.23 ± 0.11

22.2

0.001*

 % haemolysis

0.76 ± 0.35

2.21 ± 0.62

1.37 ± 0.41

17.3

0.001*

 LDH (U/L)

436.36 ± 46.31

491.10 ± 47.17

605.77 ± 61.98

33.0

0.001*

 Potassium (mmol/L)

8.05 ± 1.39

12.02 ± 1.61

11.83 ± 1.47

40.3

0.001*

 Sodium (mmol/L)

130.88 ± 4.23

133.45 ± 3.42

129.00 ± 3.51

3.74

0.035

 Chloride (mmol/L)

85.61 ± 3.91

83.37 ± 3.44

85.37 ± 2.85

0.73

0.487

Week 5

 Plasma Hb

0.20 ± 0.04

0.48 ± 0.19

0.28 ± 0.14

8.84

0.001*

 % haemolysis

1.46 ± 0.51

2.75 ± 1.00

1.78 ± 0.65

4.48

0.001*

 LDH (U/L)

536.09 ± 58.71

631.90 ± 109.29

798.00 ± 64.38

13.0

0.001*

 Potassium (mmol/L)

11.35 ± 4.46

19.48 ± 2.86

15.18 ± 1.98

8.25

0.001*

 Sodium (mmol/L)

127.64 ± 6.00

129.62 ± 5.17

124.73 ± 4.79

9.70

0.001*

 Chloride (mmol/L)

84.27 ± 4.29

77.81 ± 4.31

78.61 ± 3.44

1.22

0.309

  1. Abbreviations: LDH = Lactate dehydrogenase, SD = Standard deviation, Hb = Haemoglobin
  2. *p-values less than 0.001