Skip to main content

Table 5 Analysis of haemolytic and biochemical parameters in donor blood stored for baseline, week 1, week 3 and week 5

From: Storage related haematological and biochemical changes in Plasmodium falciparum infected and sickle cell trait donor blood

Haemolytic parameters

Baseline Mean

Week 1 Mean (%∆)

Week 3 Mean (%∆)

Week 5 Mean (%∆)

P-value

Sickle cell and malaria negative donor blood

 Plasma Hb (g/dl)

0.00

0.10

0.11(9.1)c

0.21(52.4)c

0.001*,a

 % Haemolysis

0.00

0.52

0.75(30.7)c

1.44(63.9)c

0.001*,a

 LDH (U/L)

199.40

319.20 (60.1)

428.00 (114.6)

522.70 (162.1)

0.001*,a

 Potassium (mmol/L)

4.14

5.65 (56.5)

7.72 (86.5)

10.03(142.3)

0.001*,b

 Sodium (mmol/L)

137.94

134.52 (−2.5)

130.00 (−5.7)

126.33 (−8.4)

0.001*,a

 Chloride (mmol/L)

98.66

89.06 (−3.5)

84.98 (−13.9)

83.55 (−15.3)

0.001*,b

Sickle cell trait donor blood

 Plasma Hb (g/dl)

0.00

0.24

0.37(35.1)c

0.46(47.8)c

0.001*,b

 % Haemolysis

0.00

1.16

2.08(44.2)c

2.62(55.7)c

0.001*,a

 LDH (U/L)

207.10

329.20 (59.0)

491.60 (137.4)

610.40 (194.7)

0.001*,a

 Potassium (mmol/L)

4.27

6.95 (62.8)

12.14 (184.3)

20.58 (382.0)

0.001*,a

 Sodium (mmol/L)

139.51

136.74 (−2.0)

133.67 (−4.2)

130.35 (−6.5)

0.001*,a

 Chloride (mmol/L)

99.63

90.77 (−8.9)

83.99 (− 15.7)

78.50 (−21.2)

0.001*,b

Asymptomatic malaria donor blood

 Plasma Hb (g/dl)

0.00

0.22

0.26(15.4)c

0.32(31.3)c

0.001*,a

 % Haemolysis

0.00

1.00

1.46(31.5)c

1.90(47.3)c

0.001*,a

 LDH (U/L)

192.30

418.70 (117.7)

596.60 (210.4)

806.70 (319.5)

0.001*,b

 Potassium (mmol/L)

4.38

8.38 (91.3)

11.66 (166.2)

15.01 (242.7)

0.001*,b

 Sodium (mmol/L)

140.72

135.17 (−3.9)

130.16 (−7.5)

125.60 (−10.0)

0.001*,a

 Chloride (mmol/L)

100.62

91.00 (−9.6)

85.71 (−14.8)

79.21 (−21.3)

0.001*,a

  1. Abbreviations: LDH = Lactate dehydrogenase, SD = Standard deviation, Hb = Haemoglobin
  2. *p values less than 0.001, ap-value determined by Kruskal-Wallis H test, bp-value determined by one-way ANOVA, c %Δ calculated with respect to week 1 mean values