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Table 5 Analysis of haemolytic and biochemical parameters in donor blood stored for baseline, week 1, week 3 and week 5

From: Storage related haematological and biochemical changes in Plasmodium falciparum infected and sickle cell trait donor blood

Haemolytic parameters Baseline Mean Week 1 Mean (%∆) Week 3 Mean (%∆) Week 5 Mean (%∆) P-value
Sickle cell and malaria negative donor blood
 Plasma Hb (g/dl) 0.00 0.10 0.11(9.1)c 0.21(52.4)c 0.001*,a
 % Haemolysis 0.00 0.52 0.75(30.7)c 1.44(63.9)c 0.001*,a
 LDH (U/L) 199.40 319.20 (60.1) 428.00 (114.6) 522.70 (162.1) 0.001*,a
 Potassium (mmol/L) 4.14 5.65 (56.5) 7.72 (86.5) 10.03(142.3) 0.001*,b
 Sodium (mmol/L) 137.94 134.52 (−2.5) 130.00 (−5.7) 126.33 (−8.4) 0.001*,a
 Chloride (mmol/L) 98.66 89.06 (−3.5) 84.98 (−13.9) 83.55 (−15.3) 0.001*,b
Sickle cell trait donor blood
 Plasma Hb (g/dl) 0.00 0.24 0.37(35.1)c 0.46(47.8)c 0.001*,b
 % Haemolysis 0.00 1.16 2.08(44.2)c 2.62(55.7)c 0.001*,a
 LDH (U/L) 207.10 329.20 (59.0) 491.60 (137.4) 610.40 (194.7) 0.001*,a
 Potassium (mmol/L) 4.27 6.95 (62.8) 12.14 (184.3) 20.58 (382.0) 0.001*,a
 Sodium (mmol/L) 139.51 136.74 (−2.0) 133.67 (−4.2) 130.35 (−6.5) 0.001*,a
 Chloride (mmol/L) 99.63 90.77 (−8.9) 83.99 (− 15.7) 78.50 (−21.2) 0.001*,b
Asymptomatic malaria donor blood
 Plasma Hb (g/dl) 0.00 0.22 0.26(15.4)c 0.32(31.3)c 0.001*,a
 % Haemolysis 0.00 1.00 1.46(31.5)c 1.90(47.3)c 0.001*,a
 LDH (U/L) 192.30 418.70 (117.7) 596.60 (210.4) 806.70 (319.5) 0.001*,b
 Potassium (mmol/L) 4.38 8.38 (91.3) 11.66 (166.2) 15.01 (242.7) 0.001*,b
 Sodium (mmol/L) 140.72 135.17 (−3.9) 130.16 (−7.5) 125.60 (−10.0) 0.001*,a
 Chloride (mmol/L) 100.62 91.00 (−9.6) 85.71 (−14.8) 79.21 (−21.3) 0.001*,a
  1. Abbreviations: LDH = Lactate dehydrogenase, SD = Standard deviation, Hb = Haemoglobin
  2. *p values less than 0.001, ap-value determined by Kruskal-Wallis H test, bp-value determined by one-way ANOVA, c %Δ calculated with respect to week 1 mean values