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Table 2 RBC and RBC indices storage changes in donor blood

From: Storage related haematological and biochemical changes in Plasmodium falciparum infected and sickle cell trait donor blood

RBC and RBC indices Baseline Mean Week 1 Mean (%∆) Week 2 Mean (%∆) Week 3 Mean (%∆) Week 4 Mean (%∆) Week 5 Mean (%∆) P-values
Sickle cell and malaria negative donor blood  
 RBC (×1012/L) 4.72 4.27 (−9.5) 4.08 (− 13.5) 4.03 (− 14.6) 3.98(−15.6) 4.04 (− 14.4) 0.147a
 Hb (g/dl) 13.17 11.35 (−13.8) 10.49 (− 20.3) 9.97 (− 24.3) 10.06 (−23.6) 9.74 (−26.0) 0.022a
 HCT (%) 37.54 33.52 (−10.7) 28.83 (− 23.2) 28.52 (−24.0) 28.48(− 24.1) 28.06(− 25.2) 0.013a
 MCV (fL) 75.88 76.99 (1.5) 75.34 (−0.7) 74.37 (−1.9) 74.67 (−1.6) 75.22 (− 0.9) 0.952a
 MCH (pg) 26.70 26.23 (−1.7) 27.61 (3.4) 25.85 (−3.1) 26.39 (−1.1) 26.14 (−2.0) 0.924a
 MCHC (g/dl) 32.47 31.39 (−3.3) 33.58 (3.4) 31.90 (−1.7) 32.45 (−0.6) 31.92 (−1.6) 0.932a
 RDW_CV (%) 14.14 14.14 (0.0) 14.20 (0.4) 15.02 (6.2) 14.63 (3.4) 14.76 (4.3) 0.486b
 RDW_SD (fL) 32.38 32.38 (0.0) 33.55 (3.6) 31.76 (−1.9) 32.14 (−0.7) 30.17 (−6.8) 0.756b
Sickle cell trait donor blood
 RBC (×1012/L) 4.75 4.06 (−14.5) 3.58 (−24.6) 3.57 (−24.8) 3.56 (−25.0) 3.49 (−26.5) 0.016a
 Hb (g/dl) 14.45 12.84 (−11.1) 12.47 (−13.7) 11.47 (−20.6) 11.57 (− 19.9) 11.43 (−20.8) 0.002a
 HCT (%) 39.96 36.75 (−8.0) 33.34 (−16.5) 33.29 (−16.7) 32.55 (− 18.5) 33.22 (− 16.8) 0.005a
 MCV (fL) 82.54 86.71 (5.0) 82.02 (−0.6) 81.27 (−1.5) 82.03 (− 0.61) 82.95 (0.4) 0.573a
 MCH (pg) 30.36 30.29 (−0.2) 30.39 (0.3) 28.54 (−5.9) 29.12 (−4.0) 28.43 (−6.3) 0.424a
 MCHC (g/dl) 36.75 34.99 (−4.7) 37.08 (0.9) 34.96 (− 4.8) 35.50 (−3.4) 34.30 (−6.6) 0.001a
 RDW_CV (%) 14.75 14.75 (0.0) 14.91 (1.0) 15.30 (3.7) 15.03 (1.8) 23.68 (60.5) 0.518b
 RDW_SD (fL) 35.59 35.59 (0.0) 36.54 (2.6) 33.80 (5.0) 34.06 (4.2) 31.83 (10.5) 0.082b
Asymptomatic malaria donor blood
 RBC (×1012/L) 5.00 4.48 (−10.4) 4.02 (−19.6) 4.00 (−20.0) 3.96 (−20.8) 3.72 (−25.6) 0.001*,a
 Hb (g/dl) 14.73 13.06 (−11.3) 12.12 (−17.7) 11.82 (− 19.7) 11.98 (− 18.6) 11.53 (−21.7) 0.001*,a
 HCT (%) 42.72 38.83 (−9.1) 34.04 (−20.3) 34.32 (− 19.6) 34.33 (−19.6) 33.38 (−21.8) 0.001*,a
 MCV (fL) 89.15 87.66 (−1.6) 82.04 (−7.9) 81.81 (−8.2) 82.68 (−7.2) 83.31 (−6.5) 0.067a
 MCH (pg) 30.85 29.42 (−4.6) 29.66 (−3.8) 28.13 (−8.8) 29.20 (−5.3) 29.15 (−5.5) 0.320a
 MCHC (g/dl) 35.48 33.57 (−5.3) 36.22 (2.0) 34.45 (2.9) 35.38 (−0.2) 35.01 (−1.3) 0.002b
 RDW_CV (%) 14.81 14.81 (0.0) 15.80 (6.6) 16.39 (10.6) 16.16 (9.1) 16.26 (9.7) 0.024a
 RDW_SD (fL) 36.53 36.53 (0.0) 35.75 (−2.1) 33.82 (−7.4) 34.49 (−5.5) 34.49 (−5.5) 0.267a
  1. Abbreviations: RBC = Red blood cells, Hb = Haemoglobin, HCT = Haematocrit, MCV = Mean cell volume, MCH = Mean cell haemoglobin, MCHC = Mean cell haemoglobin concentration, RDW_CV = Red cell distribution width coefficient of variation, RDW_SD = Red cell distribution width standard deviation, L = Litre, fL = Fentolitre, pg = picogram
  2. *p values less than 0.001; ap-value determined by one-way ANOVA; bp-value determined by Kruskal-Wallis H test