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Table 3 Laboratory values of biochemical parameters before and after treatment in pediatric oncology patients

From: Evaluation and characterization of tumor lysis syndrome before and after chemotherapy among pediatric oncology patients in Tikur Anbessa specialized hospital, Addis Ababa, Ethiopia

Parameters

Before treatment Median(IQR)

After treatment Median(IQR)

p value

Potassium(mmol/L)a

4.03 ± 0.74

4.40 ± 0.50

0.0001

WBC(×103/μl)

12.50(8.400–37.700)

10.00(6.250–18.825)

0.0001

LDH(IU/L)

749.00(556.95–1274.00)

524.00(371.5–863.5)

0.0001

Uric acid(mg/dl)

4.94(3.15–6.90)

6.20(4.69–6.90)

0.0001

BUN(mg/dl)

17.00(12.50–25.50)

19.00(13.00–28.25)

0.006

Creatinine(mg/dl)

0.70(0.60–0.80)

0.89(0.80–1.00)

0.0001

Sodium (mmol/l)

139.0(137.0–140.9)

139.0(138.0–141.0)

0.719

Calcium (mmol/l)

2.01(1.23–2.30)

1.21(1.09–1.90)

0.0001

Chloride (mmol/l)

105.0(101.20–109.00)

105.0(100.1–108.0)

0.671

  1. aPotassium is normally distributed, expressed as mean ± standard deviation, the rest of the variables are not normally distributed, expressed as median and IQR