Table 4 Type and frequency of immunophenotypic aberrancies detected in PB neutrophils from LR-MDS patients versus normal individuals (controls)
LR-MDS (n = 14) | Controls (n = 14) | |||
|---|---|---|---|---|
Decreased | Increased | Decreased | Increased | |
Abnormal light scatter characteristics | ||||
FSC | 10 (71%) | 1 (7%) | 0 (0%) | 0 (0%) |
SSC | 8 (57%) | 0 (0%) | 0 (0%) | 1 (7%) |
Abnormal expression of cell surface markers | ||||
CD10 | 9 (64%) | 1 (7%) | 0 (0%) | 0 (0%) |
CD11b | 10 (71%) | 1 (7%) | 0 (0%) | 1 (7%) |
CD11c | 10 (71%) | 0 (0%) | 0 (0%) | 0 (0%) |
CD13 | 4 (29%) | 1 (7%) | 0 (0%) | 0 (0%) |
CD15 | 0 (0%) | 0 (0%) | 1 (7%) | 1 (7%) |
CD16 | 6 (43%) | 0 (0%) | 0 (0%) | 0 (0%) |
CD45 | 2 (14%) | 1 (7%) | 1 (7%) | 0 (0%) |
Number of individuals with abnormal parameters | ||||
No abnormal parameters | 1 (7%) | 10 (71%) | 12 (86%) | 11 (79%) |
One abnormal parameter | 0 (0%) | 3 (21%) | 2 (14%) | 3 (21%) |
Two abnormal parameters | 2 (14%) | 1 (7%) | 0 (0%) | 0 (0%) |
Three abnormal parameters | 1 (7%) | 0 (0%) | 0 (0%) | 0 (0%) |
Four abnormal parameters | 3 (21%) | 0 (0%) | 0 (0%) | 0 (0%) |
Five abnormal parameters | 4 (29%) | 0 (0%) | 0 (0%) | 0 (0%) |
Six abnormal parameters | 2 (14%) | 0 (0%) | 0 (0%) | 0 (0%) |
Seven abnormal parameters | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) |
Eight abnormal parameters | 1 (7%) | 0 (0%) | 0 (0%) | 0 (0%) |
Nine abnormal parameters | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) |