From: Rare and unusual case of anti-factor XI antibodies in patient with plasma cell leukemia
Authors (Year of publication) | Acquired coagulation factor inhibitors | Monoclonal gammopathy types | Age (years) | sex | Type of hemorrhage | Treatment | Clinical evolution |
---|---|---|---|---|---|---|---|
Sari (2009) [7] | anti-factor VIII antibody | Multiple myeloma | 43 | F | Postoperative | VAD (vincristine, doxorubicin and dexamethasone) | favorable |
Glueck (1965) [8] | anti-factor VIII antibody | Multiple myeloma | 70 | M | cutaneous and retinal | cyclophosphamide | – |
Hoyer (1995) [9] | anti-factor VIII antibody | Multiple myeloma | 58 | F | Soft tissue, gastrointestinal | Porcine factor VIII, activated prothrombin complex concentrate; Corticosteroids, plasma exchange | deceased |
Holme (2005) [10] | anti-factor VIII antibody | Multiple myeloma | 58 | M | Postoperative | Activated prothrombin complex concentrate; Corticosteroids, cyclophosphamide | deceased |
Cowell (1996) [11] | anti-factor II antibody | Multiple myeloma | 52 | M | hematuria, Intracranial hemorrhage, epistaxis | Plasmapheresis, melphalan, prednisone, Cyclophosphamide, transplantation | deceased |
Godeau (1985) [12] | Acquired inhibitors of fibrin formation | 2 cases of Multiple myeloma | |||||
Kumar (2002) [13] | Anti-von Willebrand factor antibody | 6 cases of monoclonal gammopathies of undetermined significance, 4 cases of Waldenström’s macroglobulinemia and 1 case of Multiple myeloma | |||||
Reece (1984) [3] | anti-factor XI antibody | 3 patients with Waldenström’s macroglobulinemia |