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Table 2 Association of acquired coagulation factor inhibitors and monoclonal gammopathy: literary analysis

From: Rare and unusual case of anti-factor XI antibodies in patient with plasma cell leukemia

Authors (Year of publication)

Acquired coagulation factor inhibitors

Monoclonal gammopathy types

Age (years)

sex

Type of hemorrhage

Treatment

Clinical evolution

Sari (2009) [7]

anti-factor VIII antibody

Multiple myeloma

43

F

Postoperative

VAD (vincristine, doxorubicin and dexamethasone)

favorable

Glueck (1965) [8]

anti-factor VIII antibody

Multiple myeloma

70

M

cutaneous and retinal

cyclophosphamide

Hoyer (1995) [9]

anti-factor VIII antibody

Multiple myeloma

58

F

Soft tissue, gastrointestinal

Porcine factor VIII, activated prothrombin complex concentrate; Corticosteroids, plasma exchange

deceased

Holme (2005) [10]

anti-factor VIII antibody

Multiple myeloma

58

M

Postoperative

Activated prothrombin complex concentrate; Corticosteroids, cyclophosphamide

deceased

Cowell (1996) [11]

anti-factor II antibody

Multiple myeloma

52

M

hematuria, Intracranial hemorrhage, epistaxis

Plasmapheresis, melphalan, prednisone, Cyclophosphamide, transplantation

deceased

Godeau (1985) [12]

Acquired inhibitors of fibrin formation

2 cases of Multiple myeloma

Kumar (2002) [13]

Anti-von Willebrand factor antibody

6 cases of monoclonal gammopathies of undetermined significance,

4 cases of Waldenström’s macroglobulinemia and

1 case of Multiple myeloma

Reece (1984) [3]

anti-factor XI antibody

3 patients with Waldenström’s macroglobulinemia

  1. F: female, M: male