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Table 2 Association of acquired coagulation factor inhibitors and monoclonal gammopathy: literary analysis

From: Rare and unusual case of anti-factor XI antibodies in patient with plasma cell leukemia

Authors (Year of publication) Acquired coagulation factor inhibitors Monoclonal gammopathy types Age (years) sex Type of hemorrhage Treatment Clinical evolution
Sari (2009) [7] anti-factor VIII antibody Multiple myeloma 43 F Postoperative VAD (vincristine, doxorubicin and dexamethasone) favorable
Glueck (1965) [8] anti-factor VIII antibody Multiple myeloma 70 M cutaneous and retinal cyclophosphamide
Hoyer (1995) [9] anti-factor VIII antibody Multiple myeloma 58 F Soft tissue, gastrointestinal Porcine factor VIII, activated prothrombin complex concentrate; Corticosteroids, plasma exchange deceased
Holme (2005) [10] anti-factor VIII antibody Multiple myeloma 58 M Postoperative Activated prothrombin complex concentrate; Corticosteroids, cyclophosphamide deceased
Cowell (1996) [11] anti-factor II antibody Multiple myeloma 52 M hematuria, Intracranial hemorrhage, epistaxis Plasmapheresis, melphalan, prednisone, Cyclophosphamide, transplantation deceased
Godeau (1985) [12] Acquired inhibitors of fibrin formation 2 cases of Multiple myeloma
Kumar (2002) [13] Anti-von Willebrand factor antibody 6 cases of monoclonal gammopathies of undetermined significance,
4 cases of Waldenström’s macroglobulinemia and
1 case of Multiple myeloma
Reece (1984) [3] anti-factor XI antibody 3 patients with Waldenström’s macroglobulinemia
  1. F: female, M: male