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Table 2 Prevalence of factor V Leiden mutation and its association with SCD in Palestinian patients

From: Factor V Leiden G1691A and prothrombin G20210A mutations among Palestinian patients with sickle cell disease

Patient (n)

FV Leiden

Crude

Adjusted

G/G

G/A

A/A

OR (95% CI)

P value

OR (95% CI)

P value

SS (59)

48

11

0

9.31(2.1–61.9)

0.027

5.6 (1.91–39.4)

0.039

AS (25)

23

1

1

8.4 (1.12–64.7)

0.038

3.97 (0.51–28.6)

0.17

S/βThal (33)

26

4

3

7.2 (0.63–75.4)

0.19

3.59 (0.35–41.6)

0.26

Controls

98

18

2

1

1