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Table 3 Mean (±sd) coagulation profile parameter values of omega-3 fatty acid and hydroxyurea treated and untreated sickle cell patients (HbSS) and healthy contols

From: Coagulation profile of Sudanese children with homozygous sickle cell disease and the effect of treatment with omega-3 fatty acid on the coagulation parameters

 

Omga-3 treated

untreated

HU treated

Healthy controls

PT (sec)

17.2 ± 1.8†††

31.3 ± 11.1+++

18.2 ± 1.8xxx

14.5 ± 0.7

aPTT (sec)

38.3 ± 4.2†††

57.0 ± 11.3+++

42.8 ± 2.7xxx

37.0 ± 3.8

INR

1.2 ± 0.14†††

2.3 ± 0.90+++

1.3 ± 0.12xxx

1.01 ± 0.05

  1. †††p < 0.001 omega-3 treated versus untreated patients
  2. +++ p < 0.001 untreated patients versus healthy controls
  3. xxx p < 0.001 HU treated versus untreated patients