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Table 5 Clinical characterization of SCA and HbSC patients

From: Comparative study of sickle cell anemia and hemoglobin SC disease: clinical characterization, laboratory biomarkers and genetic profiles

Clinical characterization SCA
N = 98
HbSC
N = 52
p value
Hospitalization 90/98 (91.8%) 36/52 (69.2%) 0.001
Pneumonia 38/98 (38.8%) 22/52 (42.3%) 0.728
Splenomegaly 40/98 (40.8%) 18/52 (34.6%) 0.486
Asthma 6/98 (6.1%) 3/52 (5.8%) 1.000
Pain crises 83/98 (84.7%) 41/52 (78.8%) 0.374
Infection 36/98 (36.7%) 18/52 (34.6%) 0.859
Priapism 10/50 (20.0%) 5/22 (22.7%) 0.764
Vaso-occlusion 89/98 (90.8%) 42/52 (80.8%) 0.119
Retinopathy 3/98 (3.0%) 4/52 (7.7%) 0.236
Cholelithiasis 17/98 (17.3%) 4/52 (7.7%) 0.139
  1. Comparison of clinical events among the SCA and HbSC genotypes calculated using the Fisher’s exact test. Bold values indicate significance at p < 0.05