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Table 5 Clinical characterization of SCA and HbSC patients

From: Comparative study of sickle cell anemia and hemoglobin SC disease: clinical characterization, laboratory biomarkers and genetic profiles

Clinical characterization

SCA

N = 98

HbSC

N = 52

p value

Hospitalization

90/98 (91.8%)

36/52 (69.2%)

0.001

Pneumonia

38/98 (38.8%)

22/52 (42.3%)

0.728

Splenomegaly

40/98 (40.8%)

18/52 (34.6%)

0.486

Asthma

6/98 (6.1%)

3/52 (5.8%)

1.000

Pain crises

83/98 (84.7%)

41/52 (78.8%)

0.374

Infection

36/98 (36.7%)

18/52 (34.6%)

0.859

Priapism

10/50 (20.0%)

5/22 (22.7%)

0.764

Vaso-occlusion

89/98 (90.8%)

42/52 (80.8%)

0.119

Retinopathy

3/98 (3.0%)

4/52 (7.7%)

0.236

Cholelithiasis

17/98 (17.3%)

4/52 (7.7%)

0.139

  1. Comparison of clinical events among the SCA and HbSC genotypes calculated using the Fisher’s exact test. Bold values indicate significance at p < 0.05