Table 2 Distribution of the genotypes and alleles of the βS globin haplotype and -α3.7Kb-thalassemia in SCD
βS globin Genotype | -α3.7Kb-Thalassemia Genotype | ||||||
|---|---|---|---|---|---|---|---|
HbSC | % (N = 59) | SCA | % (N = 141) | HbSC | % (N = 59) | SCA | % (N = 141) |
BEN II | 5.1 (3) | BEN/BEN | 24.8 (35) | Absence | 84.7 (50) | Absence | 83.7 (118) |
CAR I | 35.6 (21) | BEN/CAR | 41.2 (58) | Heterozygous | 13.6 (8) | Heterozygous | 14.2 (20) |
BEN I | 47.4 (28) | CAR/CAR | 22.7 (32) | Homozygous | 1.7 (1) | Homozygous | 2.1 (3) |
CAR III | 8.5 (5) | BEN/Atypical | 5.0 (7) | ||||
CAR II | 1.7 (1) | CAR/Atypical | 3.5 (5) | ||||
BEN III | 1.7 (1) | Atypical | 2.8 (4) | ||||
βS globin Haplotype in HbSC | βS globin Haplotype in SCA | Frequency of -α3.7Kb-Thalassemia chromosome in SCD | |||||
BEN | 54.2 (32/59) | BEN | 47.9 (135/282) | Presence 0.09 (36/400) | |||
CAR | 45.8 (27/59) | CAR | 45.0 (127/282) | ||||
Atypical | 7.1 (20/282) | ||||||