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Table 2 Distribution of the genotypes and alleles of the βS globin haplotype and -α3.7Kb-thalassemia in SCD

From: Comparative study of sickle cell anemia and hemoglobin SC disease: clinical characterization, laboratory biomarkers and genetic profiles

βS globin Genotype 3.7Kb-Thalassemia Genotype
HbSC % (N = 59) SCA % (N = 141) HbSC % (N = 59) SCA % (N = 141)
BEN II 5.1 (3) BEN/BEN 24.8 (35) Absence 84.7 (50) Absence 83.7 (118)
CAR I 35.6 (21) BEN/CAR 41.2 (58) Heterozygous 13.6 (8) Heterozygous 14.2 (20)
BEN I 47.4 (28) CAR/CAR 22.7 (32) Homozygous 1.7 (1) Homozygous 2.1 (3)
CAR III 8.5 (5) BEN/Atypical 5.0 (7)     
CAR II 1.7 (1) CAR/Atypical 3.5 (5)     
BEN III 1.7 (1) Atypical 2.8 (4)     
βS globin Haplotype in HbSC βS globin Haplotype in SCA Frequency of -α3.7Kb-Thalassemia chromosome in SCD
BEN 54.2 (32/59) BEN 47.9 (135/282) Presence 0.09 (36/400)
CAR 45.8 (27/59) CAR 45.0 (127/282)  
  Atypical 7.1 (20/282)