Skip to main content

Table 1 Characteristics of study population by haemoglobin phenotype

From: Sickle-cell disease in febrile children living in a rural village of Madagascar and association with malaria and respiratory infections

Characteristics

HbAA (n = 596)

HbAS (n = 192)

HbSS (n = 19)

p

Period, quarter, N (%)

 - January-March

72 (12.1)

31 (16.1)

3 (15.8)

0.19

 - April-June

195 (32.7)

57 (29.7)

7 (36.8)

 - July-September

135 (22.6)

54 (28.1)

6 (31.6)

 - October-December

194 (32.5)

50 (26.0)

3 (15.8)

Age, months, median (IQR)

21.0 (10.5–36.0)

20.0 (9.0–36.5)

17.0 (10.0–33.0)

0.50

Age category, months, n (%)

 - 2–11

160 (26.8)

62 (32.3)

6 (31.6)

0.68

 - 12–23

152 (25.5)

45 (23.4)

5 (26.3)

 - 24–59

284 (47.7)

85 (44.3)

8 (42.1)

Gender, n (%)

 - Male

306 (51.3)

82 (42.7)

13 (68.4)

0.03

 - Female

290 (48.7)

110 (57.3)

6 (31.6)

Temperature, °C, median (IQR)

38.8 (38.6–39.4)

38.8 (38.6–39.4)

38.5 (38.0–38.7)

0.11

Height, cm, median (IQR)

78.0 (71.0–87.0)

77.0 (69.5–86.0)

74.0 (69.0–86.0)

0.18

Weight, kg, median (IQR)

9.5 (8.1–11.6)

9.3 (7.9–11.4)

8.5 (7.2–10.0)

0.61

Mid-upper arm circumference, cm, median (IQR)

140 (133–146)

140 (132–148)

128 (117–136)

0.001

Weight-for-height Z-score ≤2 SD

−1.5 (−2.2; −0.7)

−1.2 (−2.2; −0.5)

−2.2 (−3.4; −1.2)

0.02

Positive RDT malaria, n (%)

227 (38.1)

63 (32.8)

5 (26.3)

0.3

Naso-pharyngeal carriers positive detection, n (%)

 - Parechovirus

9 (1.6)

1 (0.6)

2 (11.1)

0.02

 - RSV A and B

56 (9.8)

30 (17.0)

0 (0)

0.01

 - Human coronavirus 229E

6 (1.1)

0 (0)

1 (5.6)

0.07

 - Viral coinfection

144 (25.3)

34 (19.2)

8 (44.4)

0.03

S. pneumoniae positive from blood, n (%)

11 (1.9)

3 (1.6)

1 (5.3)

0.5

  1. * HbAA, normal phenotype, HbAS sickle cell trait, HbSS sickle cell disease