Skip to main content

Advertisement

Springer Nature is making SARS-CoV-2 and COVID-19 research free. View research | View latest news | Sign up for updates

Table 4 Mean change in TSAT and serum ferritin over time by CKD stage

From: Ferumoxytol versus iron sucrose treatment: a post-hoc analysis of randomized controlled trials in patients with varying renal function and iron deficiency anemia

CKD Stage TSAT, % (SD) Ferritin, μg/L (SD)
Ferumoxytol Treatment Group Iron Sucrose Treatment Group Ferumoxytol Treatment Group Iron Sucrose Treatment Group
Stage 1 (eGFR ≥90 mL/min) (n = 280) (n = 126) (n = 280) (n = 126)
Baseline 5.8 (11.25) 4.3 (5.21) 14.1 (39.76) 15.4 (53.11)
Week 2 26.1 (19.59) 15.8 (11.90) 291.1 (192.69) 172.5 (245.93)
Week 3 24.1 (11.54) 19.8 (15.38) 179.7 (157.02) 157.3 (211.08)
Week 4 22.7 (10.95) 19.2 (13.81) 123.7 (124.20) 124.0 (211.93)
Week 5 22.9 (21.75) 19.1 (14.77) 98.3 (118.96) 96.4 (185.27)
Stage 2 (eGFR 60 to <90 mL/min) (n = 104) (n = 59) (n = 104) (n = 59)
Baseline 6.6 (5.7) 5.1 (3.47) 55.4 (138.26) 22.7 (80.21)
Week 2 26.2 (11.41) 25.8 (51.56) 442.0 (398.63) 215.0 (226.93)
Week 3 24.3 (10.39) 17.2 (7.81) 325.6 (385.93) 196.6 (212.70)
Week 4 23.9 (11.17) 18.9 (12.46) 277.9 (394.82) 166.2 (254.32)
Week 5 22.5 (10.35) 16.5 (6.66) 247.2 (471.24) 127.5 (214.99)
Stage 3 (eGFR 30 to <60 mL/min) (n = 41) (n = 33) (n = 41) (n = 33)
Baseline 13.4 (18.31) 16.1 (22.18) 106.6 (168.37) 106.5 (157.15)
Week 2 26.6 (13.27) 21.8 (22.81) 629.3 (507.21) 338.6 (296.76)
Week 3 25.0 (11.45) 18.9 (8.16) 518.1 (425.74) 373.0 (321.68)
Week 4 23.2 (11.01) 19.2 (7.78) 452.5 (443.14) 314.8 (284.35)
Week 5 23.1 (12.15) 19.4 (7.86) 426.0 (433.68) 312.0 (284.41)
Stage 4 (eGFR 15 to <30 mL/min) (n = 23) (n = 20) (n = 23) (n = 20)
Baseline 21.7 (19.41) 17.0 (6.49) 152.3 (123.03) 141.4 (158.16)
Week 2 30.6 (9.71) 24.3 (7.14) 720.7 (280.38) 520.2 (244.56)
Week 3 28.6 (13.22) 24.0 (5.85) 632.8 (324.78) 529.6 (244.92)
Week 4 32.2 (15.81) 25.7 (7.18) 552.4 (327.53) 440.5 (228.45)
Week 5 26.3 (6.34) 23.1 (5.79) 514.6 (285.12) 407.0 (231.30)
Stage 5 (eGFR <15 mL/min) (n = 38) (n = 42) (n = 38) (n = 42)
Baseline 22.3 (12.91) 21.7 (14.76) 411.3 (348.97) 359.7 (287.65)
Week 2 34.6 (16.18) 25.4 (12.87) 915.8 (372.92) 603.4 (338.87)
Week 3 32.2 (12.81) 24.7 (7.44) 959.0 (605.92) 675.2 (339.54)
Week 4 30.4 (12.57) 27.7 (13.27) 831.7 (452.94) 682.2 (391.21)
Week 5 28.7 (8.82) 27.9 (15.80) 788.4 (427.21) 618.9 (355.47)
  1. CKD chronic kidney disease, GFR glomerular filtration rate, SD standard deviation, TSAT transferrin saturation