Table 2 Graft composition and donor percentages of mononuclear cells of the peripheral blood (PBMC) and Langerhans cells (LC) after transplantation
Dog | Graft composition | Donor chimerism [%] | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
d +28 | d +56 | d +104-112 | d +140-280 | d > +280 | rejection | |||||||||
TNC [x108] | CD34 [x106] | CD3 [x107] | PBMC | LC | PBMC | LC | PBMC | LC | PBMC | LC | PBMC | LC | (day) | |
No. 1 | 2.7 | 4.0 | 0.9 | 26.3 | 0.0 | 7.7 | 0.0 | 0.0 | 0.0 | n.d. | n.d. | n.d. | n.d. | +70 |
No. 2 | 6.4 | 13.7 | 3.7 | 41.0 | 0.0 | 36.4 | 1.9 | b | b | b | died d + 60 | |||
No. 3 | 3.7 | 8.2 | 2.0 | 31.0 | 0.0 | 67.4 | 6.3 | 100.0 | 16.5 | 100.0 | 55.4 | 100.0 | 88.6 | no |
No. 4 | 1.9 | 3.6 | 1.8 | 17.8 | 0.0 | 64.1 | 41.9 | 100.0 | 88.5 | 100.0 | 90.0 | 100.0 | 95.6 | no |
No. 5 | 11.8 | 10.3 | 7.9 | 31.7 | 2.0a | 49.7 | 16.3 | 63.9 | 13.9 | n.d. | n.d. | 80.1 | 81.4 | no |
No. 6 | 6.2 | 18.2 | 3.4 | 58.1 | 0.0 | 39.9 | 0.0 | 41.1 | 12.1 | 7.7 | 17.0 | 0.0 | 35.9 | +391 |
No. 7 | 7.6 | 6.7 | 3.5 | 25.9 | 0.0 | 21.1 | 2.3 | 92.3 | 3.8 | 25.4 | 6.2 | 17.5 | 22.7 | no |
No. 8 | 2.2 | 2.6 | 1.1 | 14.7 | 7.2a | 3.1 | 7.2 | 5.0 | 5.1 | 0.0 | 7.9 | 0.0 | 5.0 | +70 |
No. 9 | 3.1 | 3.0 | 1.8 | 14.0 | 0.0 | 10.5 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | n.d. | n.d. | +91 |
Median | 3.7 | 6.7 | 2.0 | 26.3 | 0.0 | 36.4 | 2.3 | 52.5 | 8.6 | 16.6 | 12.5 | 48.8 | 58.7 | |