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Table 3 Characterization of fibrin networks formed on the surface of HMEC-1 culture by laser scanning confocal microscopy (LSCM)

From: Endothelial fibrinolytic response onto an evolving matrix of fibrin

Fibers diameter (μm)

Fg (mg/mL)

- RGD Near

- RGD Far

+ RGD Near

+ RGD Far

0.5

2.02 ± 0.05*

1.65 ± 0.05

1.49 ± 0.09*

1.72 ± 0.07

2

1.98 ± 0.12*

1.76 ± 0.12

1.99 ± 0.06*

1.62 ± 0.07

5

2.03 ± 0.65*

1.52 ± 0.33

2.00 ± 0.10

1.95 ± 0.33

Fibrin density (peaks/μm)

Fg (mg/mL)

- RGD Near

- RGD Far

+ RGD Near

+ RGD Far

0.5

0.192 ± 0.052*

0.099 ± 0.045

0.205 ± 0.051

0.160 ± 0.054

2

0.299 ± 0.029*

0.135 ± 0.035

0.270 ± 0.023*

0.152 ± 0.030

5

0.254 ± 0.030*

0.141 ± 0.057

0.282 ± 0.022*

0.138 ± 0.056

  1. Fibrin fibers diameter and density were quantified from LSCM images Values are expressed as mean (± SEM) of 3 experiments performed in duplicate
  2. *p < 0.05. Comparisons are between near the cells surface vs. far, without (−) and with (+) RGD