Table 2 Comparison between the mean of pre and post intervention values of biomarkers
From: Gum Arabic as fetal hemoglobin inducing agent in sickle cell anemia; in vivo study
Variable | Base line value Mean ± SD | Post intervention concentration value Mean ± SD | P.V. | 95 % CI |
|---|---|---|---|---|
Hb F (%) | 6·68 ± 5.44 | 7·41 ± 5·38 | .000 b | 0·431–1·028 |
Hb S (%) | 90 ± 5·15 | 89·24 ± 5·10 | .000 b | 0.455–1·043 |
Hb A2 (%) | 3·3 ± 0·52 | 3·33 ± 0.48 | 0·901 | 0·064–0·072 |
Hemoglobin (g/dL) | 7·28 ± 1·105 | 7·2638 ± 1·08 | 0·777 | −0·142–0·188 |
MCV (fL) | 85·2 ± 9.37 | 89·20 ± 12·33 | ·000 b | −2·312– − 6·058 |
PCV % | 20·56 ± 3·15 | 21·57 ± 4·29 | ·026 a | 0·124–1·902 |
MCH pg | 30·32 ± 3·87 | 30·01 ± 4·11 | 0·270 | −.2496–0·871 |
MCHC (g/dL) | 35·2 ± 2·22 | 33·4 ± 2·29 | ·000 b | 1·035–2·559 |
Reticulocyte count % | 14·412 ± 4·27 | 16·27 ± 7·03 | ·185 | −4·855–1·130 |
Platelets counts 103 /uL | 448·27 ± 144·79 | 471·36 ± 169·41 | ·346 | −71·94–25·76 |
WBCs 103 /uL | 16·72 ± 16·3 | 13·54 ± 4·68 | ·195 | −1·682–8·035 |
RBCs 106 /uL | 2·37 ± 041 | 2·42 ± 0·45 | ·170 | −0·1091–0·197 |
LDH U/L | 717·23 ± 269·95 | 643·14 ± 244·5 | ·028 a | 8·22–139·94 |
Erythropoietin IU/L | 8·74 ± 2·96 | 8·782 ± 3·92 | ·926 | −·944–·8617 |