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Table 2 Comparison between the mean of pre and post intervention values of biomarkers

From: Gum Arabic as fetal hemoglobin inducing agent in sickle cell anemia; in vivo study

Variable Base line value Mean ± SD Post intervention concentration value Mean ± SD P.V. 95 % CI
Hb F (%) 6·68 ± 5.44 7·41 ± 5·38 .000 b 0·431–1·028
Hb S (%) 90 ± 5·15 89·24 ± 5·10 .000 b 0.455–1·043
Hb A2 (%) 3·3 ± 0·52 3·33 ± 0.48 0·901 0·064–0·072
Hemoglobin (g/dL) 7·28 ± 1·105 7·2638 ± 1·08 0·777 −0·142–0·188
MCV (fL) 85·2 ± 9.37 89·20 ± 12·33 ·000 b −2·312– − 6·058
PCV % 20·56 ± 3·15 21·57 ± 4·29 ·026 a 0·124–1·902
MCH pg 30·32 ± 3·87 30·01 ± 4·11 0·270 −.2496–0·871
MCHC (g/dL) 35·2 ± 2·22 33·4 ± 2·29 ·000 b 1·035–2·559
Reticulocyte count % 14·412 ± 4·27 16·27 ± 7·03 ·185 −4·855–1·130
Platelets counts 103 /uL 448·27 ± 144·79 471·36 ± 169·41 ·346 −71·94–25·76
WBCs 103 /uL 16·72 ± 16·3 13·54 ± 4·68 ·195 −1·682–8·035
RBCs 106 /uL 2·37 ± 041 2·42 ± 0·45 ·170 −0·1091–0·197
LDH U/L 717·23 ± 269·95 643·14 ± 244·5 ·028 a 8·22–139·94
Erythropoietin IU/L 8·74 ± 2·96 8·782 ± 3·92 ·926 −·944–·8617
  1. aDifference is significant at the 0.05 level (2-tailed)
  2. bDifference is significant at the 0.01 level (2-tailed)