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Table 3 The proportion of TB patients with low, normal and high hematological profile before initiation and after completion of the intensive phase tuberculosis treatment at University of Gondar hospital, 2014

From: Effect of anti-tuberculosis drugs on hematological profiles of tuberculosis patients attending at University of Gondar Hospital, Northwest Ethiopia

Parameters

Category

Before TB treatment

After TB treatment

Reference Intervals

P-Value

RBC

Low

91 (54.2)

92 (54.8)

 

0.92

Normal

72 (42.9)

69 (41.1)

M = 4.5-6.2 × 106/ μl

F = 4.0 -5.5 × 106/μl

High

5 (3)

7 (4.2)

 

WBC

Low

24 (14.3)

31 (18.5)

 

0.262

Normal

115 (68.5)

113 (67.3)

4.0 – 10.0 × 103/μl

High

29 (17.3)

24 (14.3)

 

HCT

Low

86 (51.2)

122 (72.6)

 

0.000*

Normal

69 (41.1)

42 (25.0)

M = 40 -52 %

F =36 – 47 %

High

13 (7.7)

4 (2.4)

 

HGB

Low

92 (54.8)

121 (72)

 

0.000*

Normal

76 (45.2)

47 (28)

M = 13 – 18 g/dl

F = 12–16 g/dl

High

0 (0)

0 (0)

 

MCV

Low

13 (7.7)

10 (6)

 

0.589

normal

129 (76.8)

130 (77.4)

80 – 100 fl

high

26 (15.5)

28 (16.7)

 

MCH

low

37 (22)

18 (10.7)

 

0.000*

Normal

96 (57.1)

105 (62.5)

27 – 32 pg

High

35 (20.8)

45 (26.8)

 

MCHC

low

75 (44.6)

163 (98.2)

 

0.000*

normal

90 (53.6)

3 (1.8)

31.5 – 36 g/dl

RDW_CV

Normal

118 (70.2)

9 (5.4)

11.5 - 14.5 %

0.000*

high

50 (29.8)

159 (94.6)

 

PLT

low

22 (13.1)

25 (14.9)

 

0.01*

normal

113 (67.3)

128 (76.2)

150 - 450 × 103/μl

High

33 (19.6)

15 (8.9)

 

PDW

Normal

157 (93.5)

167 (99.4)

10 -17 %

0.000*

high

11 (6.5)

1 (0.6)

 

Lymphocyte

low

4 (2.4)

6 (3.6)

 

1.000

Normal

160 (95.2)

156 (92.9)

1.5 - 4.5 × 103/μl

high

4 (2.4)

6 (3.6)

 

Mixed cell

Normal

160 (95.2)

165 (98.2)

0.26 -1.3 × 103/μl

0.960

high

8 (4.8)

3 (1.8)

 

Neutrophil

Low

13 (7.7)

24 (14.3)

 

0.233

Normal

136 (81)

124 (73.8)

2.0 – 7.0 × 103/μl

High

19 (11.3)

20 (11.9)

 
  1. * = significant association. Hematological parameter values less than and greater than the reference intervals are categorized as low and high respectively