Effect of anti-tuberculosis drugs on hematological profiles of tuberculosis patients attending at University of Gondar Hospital, Northwest Ethiopia

Table 2 Hematological profiles of tuberculosis patients before and after initiation of anti-TB treatment at University of Gondar Teaching hospital, 2014

Variable	Before treatmentof TB Mean (SD)	After treatmentof TB Mean (SD)	P-Value
RBC/μl	4.25 × 10⁶ (0.83)	4.42 × 10⁶ (0.824)	0.072
WBC/ μl	7.5 × 10³ (3.76)	7.08 × 10³ (3.27)	0.224
Hgb (g/dl)	12.7 (2.09)	11.8 (1.68)	0.000*
HCT (%)	38.5 (2.42)	35.7 (2.31)	0.000*
MCV (fl)	88.8 (6.8)	89.7 (8.4)	0.268
MCH (Pg)	30.13 (5.0)	29.03 (3.0)	0.018*
MCHC (g/dl)	30.13 (2.91)	29.43 (7.1)	0.000*
RDW-CV	17.6 (7.09)	31.9 (5.19)	0.000*
PLT/ μl	268 × 10³ (103.2)	239.93 (99.8)	0.01*
PDW	17.01 (4.79)	15.7 (0.61)	0.001*
Lymphocyte	1.96 × 10³ (0.94)	2.08 × 10³ (1.36)	0.375
Mixed cell	0.74 × 10³ (0.422)	0.69 × 10³ (0.425)	0.272
Neutrophil	4.37 × 10³ (2.42)	4.08 × 10³ (2.31)	0.230

RBC red blood cell, WBC White blood cell, HCT Haematocrit, HGB Haemoglobin, MCV mean corpuscular volume, MCH mean haemoglobin, MCHC mean haemoglobin concentration, RDW-CV red cell distribution width, PLT platelet, PDW Platelet distribution width, fl femto litter (10⁻¹⁵L), pg pico-gram (10⁻¹²g), * significant association

ISSN: 2052-1839