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Table 1 Hematological parameters that demonstrated significant difference based on the age and sex of TB patients before initiation of anti-TB drugs compared with after completion of the intensive phase of treatment

From: Effect of anti-tuberculosis drugs on hematological profiles of tuberculosis patients attending at University of Gondar Hospital, Northwest Ethiopia

   

Before treatment

After treatment

P-value

RBC × 106/ μl

Sex

Male

4.27 ± 0.92

4.43 ± 0.92

0.235

Female

4.24 ± 0.72

4.42 ± 0.68

0.143

Age

5 – 25

4.26 ± 0.77

4.42 ± 0.89

0.320

26 – 44

4.37 ± 0.75

4.33 ± 0.68

0.747

45 – 65

4.09 ± 1.01

4.58 ± 0.92

0.030*

Hgb (g/dl)

Sex

Male

12.7 ± 2.1

11.8 ± 1.5

0.000*

Female

12.8 ± 2.1

11.8 ± 1.9

0.000*

Age

5 – 25

12.9 ± 2

11.8 ± 1.8

0.000*

26 – 44

12.9 ± 1.8

12 ± 1.4

0.001*

45 – 65

12.4 ± 2.5

11.5 ± 1.8

0.000*

HCT (%)

Sex

Male

38.6 ± 6

35.8 ± 4.4

0.000*

Female

38.9 ± 5.5

35.7 ± 5.4

0.000*

Age

5 – 25

39.1 ± 5.7

35.7 ± 5.5

0.000*

26 – 44

38.9 ± 4.9

36.6 ± 4

0.001*

45 – 65

37.9 ± 6.8

34.7 ± 5

0.000*

MCV (fl)

Sex

Male

88.4 ± 6.9

89.4 ± 9.1

0.036*

Female

89.4 ± 6.7

90.9 ± 5.1

0.143

Age

5 – 25

89.4 ± 7.3

90.2 ± 5.1

0.486

26 – 44

88.3 ± 5.8

91.2 ± 5.8

0.013*

45 – 65

88.7 ± 7.6

90.4 ± 5.2

0.241

MCH (pg)

Sex

Male

28.9 ± 3.3

29.6 ± 2.3

0.143

Female

29.2 ± 2.6

30.1 ± 2

0.040*

Age

5 – 25

29.3 ± 3

29.7 ± 2.1

0.427

26 – 44

29.1 ± 3.1

29.7 ± 2.5

0.253

45 – 65

28.5 ± 3

30 ± 2

0.012*

MCHC (%)

Sex

Male

32.7 ± 2

32.7 ± 1.3

0.878

Female

32.6 ± 1.4

33.1 ± 1.1

0.049*

Age

5 – 25

32.6 ± 1.6

32.9 ± 1.3

0.357

26 – 44

33 ± 1.9

32.7 ± 1.3

0.390

45 – 65

32.2 ± 1.6

33.1 ± 1

0.003*

RDW CV (%)

Sex

Male

14.4 ± 1.4

14.2 ± 1.2

0.311

Female

14.5 ± 1.7

13.9 ± 1.2

0.02*

Age

5 – 25

14.4 ± 1.4

14.1 ± 1.3

0.143

26 – 44

14.3 ± 1.4

14.1 ± 1.2

0.477

45 – 65

14.6 ± 1.8

14 ± 1.1

0.059

PLT × 103/μl

Sex

Male

267 ± 106

232 ± 109

0.031*

Female

270 ± 101

250 ± 86

0.169

Age

5 – 25

258 ± 105

250 ± 116

0.697

26 – 44

274 ± 101

246 ± 72

0.085

45 – 65

275 ± 105

216 ± 108

0.006*

  1. * = significant association