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Table 3 Median (IQR) factor utilization (u/kg/year) before and during observation period

From: Prophylaxis in older Canadian adults with hemophilia A: lessons and more questions

  All subjects (n = 206) 18-39 years (n = 151) ≥40 years (n = 55) p value
Before 2057 (1239;3338) 2035 (1239;3343) 2143 (1200;3307) NS
During 2341 (1336;3650) 2437 (1601;3650) 1702 (630;3755) 0.027
  Prophylaxis 2707 (2049;3989) 2625 (2065;3857) 3447 (1931;4938)  
  On-demand 1066 (446;1718) 1371 (545;2087) 560 (266;1139)  
  (p value) (<0.001) (<0.001) (<0.001)