Figure 1

Analysis of intracytoplasmic cytokine profile of monocytes and neutrophils from the peripheral blood of blood donors (BDs; white bars), patients with HA who are negative for anti-FVIII inhibitors (HAα-FVIII[−]; light gray bars), and patients with HA who are positive for anti-FVIII inhibitors (HAα-FVIII[+]; dark gray bars). Statistical significance at p < 0.05 is represented by letters “a”, “b”, and “c” for comparisons with BDs, HAα-FVIII(−) patients, and HAα-FVIII(+) patients, respectively. The number of gated neutrophils and monocytes ranged from 19,500 to 22,500 and from 1,200 to 2,100, respectively.