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Table 1 Gene candidates for skin manifestation of cGVHD

From: Combined meta-analysis of systemic effects of allogeneic stem cell transplantation and systemic sclerosis

Gene

Symbol

Gene

Lympho-cyte

Stem cell transplantation

Graft versus host disease

Systemic sclerosis

Jun proto-oncogene*

JUN

13683

1546

83

16

33

Lymphotoxin beta receptor

LTBR

94

93

6

9

0

CD48 molecule

CD48

136

275

29

4

0

Cyclin D1

CCND1

7324

424

76

3

1

FBJ murine osteosarcoma viral oncogene homolog

FOS

15253

836

31

1

10

Interleukin 16

IL16

129

242

2

1

1

CDC-like kinase 1

CLK1

27

0

1

1

0

Matrix metallopeptidase 2 (gelatinase A)

MMP2

906

45

30

0

4

DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked

DDX3X

57

2

2

0

0

GRB2-associated binding protein 1

GAB1

114

23

1

0

0

FBJ murine osteosarcoma viral oncogene homolog B

FOSB

522

22

1

0

0

Tumor necrosis factor, alpha-induced protein 8

TNFAIP8

14

4

1

0

0

Prosaposin

PSAP

178

11

0

0

1

SATB homeobox 1

SATB1

146

61

0

0

0

Dual specificity phosphatase 1

DUSP1

392

18

0

0

0

Ubiquitin specific peptidase 18

USP18

71

7

0

0

0

Dnaj (Hsp40) homolog, subfamily B, member 1

DNAJB1

67

7

0

0

0

Elongation factor, RNA polymerase II, 2

ELL2

22

6

0

0

0

Serum/glucocorticoid regulated kinase

SGK

211

3

0

0

0

Retinoid X receptor, alpha

RXRA

77

3

0

0

0

Zinc finger protein 331

ZNF331

18

2

0

0

0

Protein kinase, AMP-activated, alpha 1 catalytic subunit

PRKAA1

77

1

0

0

0

Methionine sulfoxide reductase B1

SEPX1

5

1

0

0

0

ARP6 actin-related protein 6 homolog (yeast)

ACTR6

1

0

0

0

0

Ubiquitin specific peptidase 47

USP47

1

0

0

0

0

  1. *Bolded are genes related to fibroblast proliferation.