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Figure 5 | BMC Hematology

Figure 5

From: Combined meta-analysis of systemic effects of allogeneic stem cell transplantation and systemic sclerosis

Figure 5

Pathway distribution of cGVHD-SSc gene candidates. The detailed output of pathway analysis was queried against 25 gene candidates (main circle), which are potentially associated with the skin manifestation of cGVHD. Genes were grouped according to involvement in three major pathways (Figure 5): connective tissue development and function (solid oval), skeletal and muscular system development function (dotted oval), and immune cell trafficking (dashed oval). The known cGVHD genes are bolded. The candidates, which were reported in the original aSCT study, are underscored. Genes that were identified by our eGWAS studies (Figures 1) are highlighted by grey boxes.

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