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Table 2 Coagulation and Plasminogen System Parameters in B6 and A/J inbred mouse strains

From: Genetic background determines response to hemostasis and thrombosis

 

B6

A/J

Prothrombin Time (sec)

17 ± 1

18 ± 1

aPTT Time (sec)

66 ± 3

61 ± 7

Plasminogen (μg/mL)

131 ± 5

176 ± 9**

Fibrinolytic Activity (nM)

2.6 ± 0.1

3.0 ± 0.1*

PAI-1 Antigen (ng/mL)

7.4 ± 0.7

7.5 ± 0.7

PAI-1 Activity (U/mL)

185 ± 10

229 ± 8**

α2-antiplasmin (μg/mL)

170 ± 6

195 ± 5**

Fibrinogen (ng/mL)

1.6 ± 0.04

1.7 ± 0.05*

  1. Values are the mean ± SEM. *P < 0.05, **P < 0.01. n = 5–8.