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Table 2 FA gene expression ratios in Fancc -/- hematopoietic cell population as compared to Fancc+/+ cells

From: Fanconi anemia genes are highly expressed in primitive CD34+hematopoietic cells

 

BM

Lin-Thy1.2-

LTS-CD34+

LTS-CD34-

Fanca

5.1 ↑

7.0 ↑

0.45

1.3

Fancd1/Brca2

3.3↑

2.6↑

2.9

0.58

Fancd2

4.3 ↑

0.18 ↓

0.76

1.5

Fance

0.75 ↓

0.95

1.5

0.37

Fancf

1.1

1.1

0.46

0.79

Fancg

1.8

1.3

0.06 ↓

-

Brca1

7.0↑

2.5↑

1.7

1.7

  1. ↑ Significant increased expression levels in Fancc -/- cells; ↓ Significant decreased expression levels in Fancc -/- cells -: Gene expression not detected neither in Fancc +/+ nor Fancc -/- cells
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BMC Hematology

ISSN: 2052-1839

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