Table 2 Differentially expressed genes between FA and control cells after cisplatin treatment.

Gene Description

GenBank accession no.

Change*

C-type lectin, AICL

X96719

Up 1 h in WT

Integral membrane protein, LIG-1

W25875

Up 1 h in FA

Integral membrane protein, SIGMAR1

U79528

NC

Growth factor

Insulin growth factor binding protein 2, IGFBP-2

S37730

NC

Endothelial cell growth factor, platelet-derived, ECGF1

M63193

Down 24 h in WT

IL18R1/IL-1RRP

U43672

NC

BMP-4

U43842

Down 1 h in FA

IL10R

U00672

NC

Notch ligand, JAGL1

AF003837

NC

Signal transduction

Adapter molecule in signal transduction, DOC1

U53445

Up 24 h in FA

SRC family tyrosine kinase, FYN

M14333

Down 24 h in FA

Protein tyrosine phosphatase, PTPG

U46116

Down >7 h in FA

Regulator of G-protein signaling, G0S8/RGS

L13463

Up 1 h in FA

Regulator of G-protein signaling, GIPC/RGS19IP1

AF089816

Up 24 h in WT

Mitogen-activated protein kinase kinase kinase kinase 4, MAP4K4

AB014587

NC

Serine/threonine kinase, KIAA0623

AB014523

NC

Related to the N-terminus of TRE, RNTRE

D13644

NC

Related to intracellular calcium signaling, HOMER-1B

Y17829

NC

MEK6/MKK6

U39657

NC

Zinc finger protein, LOC58500

X16282

NC

LYT10/NF-kB2

U20816

NC

Dual specific tyrosine kinase, DYRK2

Y13493

NC

Phospholipase C beta 2, PLCB2

M95678

NC

Containing Pleckstrin homology domain, KIAA0763

AB18306

NC

Vesicular Rab-GAP/TBC-containing protein, AD3

AB024057

NC

Calcium-binding protein, S100C/Calgizzarin

D38583

NC

Transcription factor

Transcript homolog, MEST/PEG1

D78611

NC

Myotubularin related protein 2, MTMR2

AB028996

NC

Homeobox protein related to skeletal development, MSX1

M97676

NC

Transcription factor, MRG1

U65093

NC

Homeobox, PRH/PRHX

L16499

NC

MSX2/MSH/HOX8

D89377

NC

Transcriptin activating factor, CREBP

L05515

NC

Transcription coactivator, TCFEC/TFECL

D43945

NC

Putative transcription regulator, CARM-1

AI660225

Down 7 h in FA

Cell cycle

CDC25A

M81933

NC

Apoptosis

Similar to rat CIPHAR-1, DKFZp564O0823

AL080121

NC

BCLX

Z23115

NC

Protease inhibitor, PLANH2/PAI2

Y00630

NC

Vanin-2, VNN2

D89974

Down 24 h in WT

DNA repair/Chromosome regulator

Similar to DNA helicase, FLJ10738

W28620

NC

HPARG

AF005043

NC

BAF170

U66616

NC

PMS2

U13696

NC

Intracellular processing

Ubiquitin protein ligase, E6-AP

AF002224

Up >1 h in WT

Putative splicing factor, DOM3Z

AF059252

Down >7 h in FA

CBP2/TAFI

M75106

NC

Uronyl 2-sufotransferase

AB020316

NC

Miscellaneous

Procollagen-proline, 2-oxoglutarate 4-dioxygenase, P4HA2

U90441

NC

Unknown, FLJ21174

AA149307

NC

Unknown, expressed in macrophage

X89059

Up >1 h FA

Clathrin light chain b

X81637

NC

Related to lipodystrophy, LPIN2

D87436

NC

ME1

U43944

NC

Unknown, KIAA0090

D42044

Down 24 h in WT

Unknown, DKFZp564I122

AL080062

NC

Unknown, KIAA0241

D87682

NC