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Table 5 Distribution of the Ggamma -158 C→T and AgammaT mutations in thalassemic patients and in control subjects.

From: Factors regulating Hb F synthesis in thalassemic diseases

GROUP OF PATIENTS

Allele frequencies

 

Ggamma-158 C→T

AgammaT

Sub-silent beta tal int

8.6

27.3

Evident beta tal int

18.3

26.6

beta tal int with genotype triplicated alpha + beta tal

16.6

17.6

Hb H disease

37.5

5.5

Tal major

2.1

35.4

Normal controls

25.0

18.0