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Table 1 Hematologic and hemoglobinic data and Epo levels in thalassemic patients and control subjects.

From: Factors regulating Hb F synthesis in thalassemic diseases

Group of patients

N. cases

Hb g/dl

Hb F %

EPO mU/l

Glob. synth. alpha/non-alpha

Ret. ‰

Sub-silent beta thal int

33

10.1 ± 1.0

20.5 ± 18.2 3.0 → .70.6

41.22 ± 32.00 11.66 → 136.6

2.10

31

Evident beta thal int

41

8.3 ± 1.16

33.40 ± 28.04 6.80 → 85.0

95.83 ± 64.33 17.84 → 218.97

2.20

60

beta thal int in double heterozygous beta thal + triplicated alpha

58

10.0 ± 1.38

5.15 ± 3.9 2.0 → 19.3

28.45 ± 17.11* 7.85 → 60.72

2.50

30

Hb H disease

15

9.4 ± 1.2

< 1

32.88 ± 12.11**

0.52

28

Thal major

24

10.4 ± 1.0

7.7 ± 8.5*** 1.60 → 40.9

46.83 ± 40.78 9.82 → 129.59

 

17

Healthy non-thal subjects

53

14.4 ± 1.1

<1

11.90 ± 3.3

~1.0

3

Iron-deficient non-thal subjects

42

8.7 ± 1.2

<1

160.10 ± 312.6 2.7 → 1960.0

 

8

  1. * The measurement of Epo has been detected only in 17 patients. ** The measurement of Epo has been detected only in 10 patients. *** This value is not informative as patients were routinely transfused.