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Table 3 Univariate and multivariable linear regression analyses of association between clinical and demographic characteristics and total PEDsQL scores in thalassemia patients and parents

From: Health related quality of life in Middle Eastern children with beta-thalassemia

Characteristic Total PEDSQL score (patients) Total PEDSQL score (parents)
  Univariateβ (95% CI) Multivariableβ (95% CI) Univariateβ (95% CI) Multivariableβ (95% CI)
Sex 1.49 (95% CI −9.09 to 12.07) p = 0.783 - 4.40 (95% CI −5.81 to 14.61) p = 0.401 -
Age at diagnosis 0.22 (95% CI −0.20 to 0.63) p = 0.311 - −0.01 (95% CI −0.42 to 0.39) p = 0.959 -
Age at first transfusion 0.15 (95% CI −0.22 to 0.53) p = 0.423 - −0.12 (95% CI −0.48 to 0.25) p = 0.528 -
Age at start of iron chelation −0.17 (95% CI −0.33 to 0) p = 0.046 −0.17 (95% CI −0.33 to 0) p = 0.046 −0.21(95% CI −0.36 to –0.06) p = 0.007 −0.21(95% CI −0.36 to –0.06) p = 0.007
Transfusion Frequency 7.04 (95% CI −5.56 to 19.65) p = 0.278 - 3.30 (95% CI −9.03 to 15.63) p = 0.602 -
Hepatomegaly 1.46 (95% CI −11.41 to 14.32) p = 0.278 - 5.11 (95% CI −7.29 to 17.51) p = 0.423 -
Hepatitis −2.91 (95% CI −13.88 to 8.06) p = 0.605 - −2.21 (95% CI 12.87 to 8.45) p = 0.686 -
Ferritin (>1300) 10.77 (95% CI −1.66 to 23.20) p = 0.095 - 3.05 (95% CI −9.28 to 15.38) p = 0.629  
Iron Chelation 6.24 (95% CI −6.40 to 18.87) p = 0.337 - 10.95 (95% CI −1.08 to 22.98) p = 0.080 -