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Table 3 Univariate and multivariable linear regression analyses of association between clinical and demographic characteristics and total PEDsQL scores in thalassemia patients and parents

From: Health related quality of life in Middle Eastern children with beta-thalassemia

Characteristic

Total PEDSQL score (patients)

Total PEDSQL score (parents)

 

Univariateβ (95% CI)

Multivariableβ (95% CI)

Univariateβ (95% CI)

Multivariableβ (95% CI)

Sex

1.49 (95% CI −9.09 to 12.07) p = 0.783

-

4.40 (95% CI −5.81 to 14.61) p = 0.401

-

Age at diagnosis

0.22 (95% CI −0.20 to 0.63) p = 0.311

-

−0.01 (95% CI −0.42 to 0.39) p = 0.959

-

Age at first transfusion

0.15 (95% CI −0.22 to 0.53) p = 0.423

-

−0.12 (95% CI −0.48 to 0.25) p = 0.528

-

Age at start of iron chelation

−0.17 (95% CI −0.33 to 0) p = 0.046

−0.17 (95% CI −0.33 to 0) p = 0.046

−0.21(95% CI −0.36 to –0.06) p = 0.007

−0.21(95% CI −0.36 to –0.06) p = 0.007

Transfusion Frequency

7.04 (95% CI −5.56 to 19.65) p = 0.278

-

3.30 (95% CI −9.03 to 15.63) p = 0.602

-

Hepatomegaly

1.46 (95% CI −11.41 to 14.32) p = 0.278

-

5.11 (95% CI −7.29 to 17.51) p = 0.423

-

Hepatitis

−2.91 (95% CI −13.88 to 8.06) p = 0.605

-

−2.21 (95% CI 12.87 to 8.45) p = 0.686

-

Ferritin (>1300)

10.77 (95% CI −1.66 to 23.20) p = 0.095

-

3.05 (95% CI −9.28 to 15.38) p = 0.629

 

Iron Chelation

6.24 (95% CI −6.40 to 18.87) p = 0.337

-

10.95 (95% CI −1.08 to 22.98) p = 0.080

-